Clinical Outcomes of Patients With Deferred Revascularization Based on FFR and iFR Negative Coronary Artery Lesions.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

345 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-10

Study Completion Date

2021-08-20

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The objective is to assess long-term clinical outcomes of patients in whom intervention of coronary lesions was deferred due to negative fractional flow reserve (FFR) and negative Instantaneous wave-free ratio (iFR) in a real-world patient population and to identify factors associated with deferred target lesion failure.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

A Hospital-Based Registry of Preventive Cardiology Clinics

NCT06503341

Cardiovascular Morbidity Cardiovascular Risk Assesment Primary Prevention CVD

RECRUITING

Screening and Secondary Prevention Rheumatic Heart Disease Study

NCT05991219

Rheumatic Heart Disease

RECRUITING

Predictors of an Unfavorable Outcome in Patients With Heart Failure

NCT04753814

Heart Failure

COMPLETED NA

Prognostic Model Heart Failure

NCT06414928

Heart Failure Acute

RECRUITING

Frailty Score Assessment for Elderly Patients Undergoing Cardiac Resynchronization Therapy

NCT02369419

Heart Failure

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Fractional flow Reserve (FFR) evaluates functional significance of stenosis in intermediate coronary lesions. Instantaneous wave-free ratio (iFR) is considered noninferior to FFR and does not require adenosine administration.

This study was done to assess long-term clinical outcomes and factors associated with target vessel revascularization (TVR) in patients with deferred revascularization based on negative FFR and iFR.

Retrospective analysis of medical records of 345 patients with deferred revascularization at a tertiary care hospital , from January 2012 to January 2020 will be done.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Coronary Artery Disease

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Fractional flow reserve, instantaneous wave-free Ratio

Clinical outcomes observed for patients with moderate coronary lesions in whom coronary revascularization was deferred due to a negative physiologic study.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients who had intermediate to severe coronary lesions on coronary angiogram.
* Patients who had negative FFR \>0.80 or iFR \>0.89 and did not undergo immediate or planned revascularization on basis of negative physiologic assessment.

Exclusion Criteria

* Patients younger than 18 years of age or those having positive FFR/iFR values irrespective of revascularization status were excluded.
* Similarly, those who were lost to follow up and could not be traced via telephonic or were also excluded.

Eligible Sex

ALL

Accepts Healthy Volunteers

No