HIV Indicator Diseases in Hospital and Primary Care

NCT ID: NCT05225493

Last Updated: 2022-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

1500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-01

Study Completion Date

2024-05-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Patients are frequently evaluated by physicians for medical work-up of HIV indicator conditions in hospital and in primary care at the general practitioner. Testing for HIV is indicated with HIV indicator disorder but often omitted in clinical work-up. Besides the fact that HIV testing is forgotten, there are other reasons such as an underestimation of the risk of HIV in the event of indicator disorders, stigma and difficulties in discussing the test with a patient. Also and more relevant for primary care than for the hospital, practical challenges can exist for a patient to go to a laboratory, or costs are a hurdle.

This project focuses on improving HIV indicator condition driven testing in different settings of the HIV epidemic, initially in the Netherlands as low HIV prevalence setting followed by an assessment of its benefit in different international settings. A specific focus will also be on the Rotterdam area in the Netherlands which has a high prevalence of undiagnosed HIV in the Netherlands. The ultimate aim is to decrease the number of undiagnosed HIV in populations, improve the 90-90-90 HIV cascade of care goals particularly its first pillar, and to help supporting the UNAIDS goal to end HIV/AIDS

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

HIV Infections Primary Health Care Acquired Immunodeficiency Syndrome Sexually Transmitted Diseases, Viral Herpes Zoster Dermatitis, Seborrheic Pneumonia Infectious Mononucleosis Psoriasis Candida Infection Lymphadenopathy Uterine Cervical Dysplasia Weight Loss Diarrhea Chronic Leukopenia Thrombocytopenia AIDS Defining Illness HIV Indicator Condition

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Hospital

Medical specialists in hospitals and their patients aged 18 years and older in the participating hospitals who are diagnosed there with an HIV indicator condition.

Peer to peer feedback

Intervention Type BEHAVIORAL

HIV experts contact non-HIV specialised treating physicians on individual patient care to recommend HIV testing

Primary care

General practitioners and their patients aged 18 years and older in the participating general practices who are diagnosed there with an HIV indicator condition.

Peer to peer feedback

Intervention Type BEHAVIORAL

HIV experts contact non-HIV specialised treating physicians on individual patient care to recommend HIV testing

HIV rapid test

Intervention Type DIAGNOSTIC_TEST

Free HIV rapid tests are provided to non-HIV specialised treating physicians to use in individual patient care in patients at risk of HIV

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Peer to peer feedback

HIV experts contact non-HIV specialised treating physicians on individual patient care to recommend HIV testing

Intervention Type BEHAVIORAL

HIV rapid test

Free HIV rapid tests are provided to non-HIV specialised treating physicians to use in individual patient care in patients at risk of HIV

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Diagnosis of an HIV indicator conditions.

Exclusion Criteria

* Below 18 years of age
* Recent HIV test (\< 12 months, except for mononucleosis-like disease and STDs)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Huisartspraktijk Gezondheidscentrum Mathenesserlaan

UNKNOWN

Sponsor Role collaborator

TU Delft department of Artificial Intelligence and MyTomorrows

UNKNOWN

Sponsor Role collaborator

Huisartsen Groep Rotterdam

UNKNOWN

Sponsor Role collaborator

AwareHIV Project Group

UNKNOWN

Sponsor Role collaborator

Huisartspraktijk Handellaan

UNKNOWN

Sponsor Role collaborator

Huisartspraktijk Leerdam

UNKNOWN

Sponsor Role collaborator

Huisartspraktijk Capelle ad IJssel

UNKNOWN

Sponsor Role collaborator

Leiden University Medical Center

OTHER

Sponsor Role collaborator

Maasstadziekenhuis

UNKNOWN

Sponsor Role collaborator

Rijnstate Hospital

OTHER

Sponsor Role collaborator

Medical Center Haaglanden

OTHER

Sponsor Role collaborator

Erasmus Medical Center

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Casper Rokx

MD PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Carlijn CCE Jordans

Rotterdam, South Holland, Netherlands

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Netherlands

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Casper Rokx, MD PhD

Role: CONTACT

+31681336328

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Carlijn C Jordans, PhD

Role: primary

+31634304279

Maartje M Wagemaker, RN

Role: backup

+31631145074

References

Explore related publications, articles, or registry entries linked to this study.

Jordans CCE, Niemantsverdriet-Rokx L, Struik JL, van der Waal EC, van der Voorn PVJM, Bakker N, Verbon A, Bindels PJE, Rokx C. Implementing HIV teams to improve HIV indicator condition-guided testing in general practitioner centers in the Netherlands. BMC Prim Care. 2024 Dec 27;25(1):440. doi: 10.1186/s12875-024-02666-0.

Reference Type DERIVED
PMID: 39731054 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

MEC-2021-0277

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.