Targeting the Carotid Bodies to Reduce Disease Risk Along the Diabetes Continuum
NCT ID: NCT05219994
Last Updated: 2023-07-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
22 participants
INTERVENTIONAL
2020-09-09
2023-05-10
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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Oral Glucose Tolerance Test
Subjects will consume a 75 g glucose drink within 1-min and monitored for 2 hours.
Hyperoxia Exposure
2 hours of hyperoxia exposure during OGTT
Normoxia Exposure
2 hours of normoxia exposure during OGTT
Interventions
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Hyperoxia Exposure
2 hours of hyperoxia exposure during OGTT
Normoxia Exposure
2 hours of normoxia exposure during OGTT
Eligibility Criteria
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Inclusion Criteria
* type 2 diabetes
* BMI 18-40 kg/m2,
* non-pregnant,
* non-breastfeeding,
* non-nicotine users.
Exclusion Criteria
* renal or hepatic diseases;
* active cancer;
* autoimmune diseases;
* immunosuppressant therapy;
* excessive alcohol consumption (\>14 drinks/week);
* current nicotine use;
* foot ulcers;
* diabetic neuropathy;
* medication directly influencing sympathetic nervous system activity
18 Years
65 Years
ALL
Yes
Sponsors
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University of Missouri-Columbia
OTHER
Responsible Party
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Jacqueline K Limberg, PhD
Assistant Professor
Principal Investigators
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Jacqueline Limberg, Ph.D.
Role: PRINCIPAL_INVESTIGATOR
University of Missouri-Columbia
Locations
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University of Missouri
Columbia, Missouri, United States
Countries
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Other Identifiers
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2018486
Identifier Type: -
Identifier Source: org_study_id
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