Fitness Assessment in Young Adults Recovered From Lymphoma
NCT ID: NCT05188755
Last Updated: 2022-12-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
44 participants
INTERVENTIONAL
2022-01-01
2022-12-06
Brief Summary
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Although the benefits of PA in oncology are now well identified for adult populations, studies are still rare in the population of children, adolescents and young adults, and the results are still difficult to generalize. As a result, there is no recommendation on the practice of physical activity in pediatric oncology or adolescents and young adults and the levels of physical activity of cured patients remain lower than those of the general population.
Fitness is a marker of health in adults as well as in adolescents. Physical condition is a set of components such as cardiorespiratory capacity (transport and use of O2), body composition (distribution of bone, muscle and fat masses) and muscle function (strength, power, fatigue, energy metabolism) .
The investigators hypothesize that, compared to young adults, recovered from lymphoma are expected to exhibit impaired physical condition, due to physical deconditioning.
Detailed Description
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Conditions
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Keywords
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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Healthy controls
sex and age matched healthy controls
Indirect calorimetric test during submaximal exercise
* metabolic evaluation by indirect calorimetry at rest and during exercise
* evaluation of cardiac output
* peripheral quantitative computed tomography (pQCT) of the muscle cross section
* evaluation of body composition
* assessment of physical capacity (chair test and 3 min step-test)
* blood test
* assess the level of physical activity
young adults recovered from lymphoma or Hodgkin's disease
young adults recovered from lymphoma or Hodgkin's disease
Indirect calorimetric test during submaximal exercise
* metabolic evaluation by indirect calorimetry at rest and during exercise
* evaluation of cardiac output
* peripheral quantitative computed tomography (pQCT) of the muscle cross section
* evaluation of body composition
* assessment of physical capacity (chair test and 3 min step-test)
* blood test
* assess the level of physical activity
Interventions
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Indirect calorimetric test during submaximal exercise
* metabolic evaluation by indirect calorimetry at rest and during exercise
* evaluation of cardiac output
* peripheral quantitative computed tomography (pQCT) of the muscle cross section
* evaluation of body composition
* assessment of physical capacity (chair test and 3 min step-test)
* blood test
* assess the level of physical activity
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* giving free and informed consent
* Hodgkin lymphoma or non-Hodgkin lymphoma in the healing stage
* Cured (defined by an undetectable disease at the end of treatment) for at least one year and maximum 6 years of lymphoma or Hodgkin's disease
Exclusion Criteria
* People under judicial protection
* Treatment with systemic glucocorticoids for more than a week, during the 30 days preceding the tests
* Medical contraindication to the practice of physical exercise
* Any pathologies (other than the history of lymphoma for the cases) likely to affect the metabolism or the muscle mass
* Any treatment that may have an influence on the energy metabolism
* Active infection
* Pregnant, breastfeeding, or likely to be
* Subject's refusal to participate
18 Years
25 Years
ALL
Yes
Sponsors
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University Hospital, Clermont-Ferrand
OTHER
Responsible Party
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Principal Investigators
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Justina Kanold
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Clermont-Ferrand
Locations
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CHU de Clermont-Ferrand
Clermont-Ferrand, , France
Countries
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Other Identifiers
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2021-A02184-37
Identifier Type: OTHER
Identifier Source: secondary_id
RBHP 2021 KANOLD
Identifier Type: -
Identifier Source: org_study_id