Level of Physical Activity and Its Associations With Fatigue and Quality of Life in Multiple Myeloma Survivors

NCT ID: NCT02078518

Last Updated: 2014-03-05

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 75 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2013-09-30

Brief Summary

The purpose of this study is to gives understanding to level of physical activity, occurrence of fatigue and quality of life amongst multiple myeloma survivors in the local setting. As multiple myeloma survival improves, it is vital to focus on interventions that will help to maximize QOL. A positive correlation may suggest that exercise is such an intervention.

The hypothesis are multiple myeloma survivors are performing low levels of physical activity. Higher levels of physical activity will be associated with higher levels of QOL and lower fatigue levels.

Detailed Description

Multiple myeloma its associated treatment often result in persistent symptoms such as fatigue, pain, neuropathy and diminished functional performance that can affect the survivor's quality of life (QOL). And as survival for multiple myeloma continues to improve, physical activity may be a supportive therapy that can help to address the multitude of QOL concerns. Physical activity is a modifiable behavior, and has been proposed as an important non-pharmacologic intervention to improve health-related outcomes among cancer survivors. The American College of Sports Medicine examined evidence of the impact of physical activity in cancer survivors, and concluded that physical activity is safe for cancer patients, both during and after cancer treatment, and may lead to improved physical functioning, decreased physical fatigue, and improved QOL in a number of cancer survivor groups, including hematopoietic malignancies. While a small number of studies have suggested that exercise may reap benefits in QOL and fatigue in multiple myeloma survivors, none were conducted in the local context.Given the limited evidence, the primary objectives of this preliminary study is to estimate the prevalence of physical activity among a local sample of multiple myeloma survivors, and to investigate its associations with reported fatigue and quality of life.

Conditions

Multiple Myeloma

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: PROSPECTIVE

Study Groups

Multiple Myeloma

Questionnaires will be given to patients for completion.

Questionnaires

Intervention Type: OTHER

Interventions

Questionnaires

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Diagnosis of Multiple Myeloma
• Able to complete questionnaires

Exclusion Criteria

• Unable to complete questionnaires

• Minimum Eligible Age: 21 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

National University Hospital, Singapore

OTHER

Sponsor Role: lead

Responsible Party

Haematology-Oncology

Chng Wee Joo

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

National University Hospital

Singapore, , Singapore

Site Status: RECRUITING

Countries

Singapore

Central Contacts

Wee Joo Chng, MB ChB, PhD, FRCP

Role: CONTACT

wee_joo_chng@nuhs.edu.sg

(65) 6779 5555

Facility Contacts

Wee Joo Chng, MB ChB, PhD, FRCP

Role: primary

wee_joo_chng@nuhs.edu.sg

(65) 6779 5555

References

Jones LW, Courneya KS, Vallance JK, Ladha AB, Mant MJ, Belch AR, Stewart DA, Reiman T. Association between exercise and quality of life in multiple myeloma cancer survivors. Support Care Cancer. 2004 Nov;12(11):780-8. doi: 10.1007/s00520-004-0668-4.

Reference Type: BACKGROUND

PMID: 15322968 (View on PubMed)

Coleman EA, Goodwin JA, Coon SK, Richards K, Enderlin C, Kennedy R, Stewart CB, McNatt P, Lockhart K, Anaissie EJ, Barlogie B. Fatigue, sleep, pain, mood, and performance status in patients with multiple myeloma. Cancer Nurs. 2011 May-Jun;34(3):219-27. doi: 10.1097/NCC.0b013e3181f9904d.

Reference Type: BACKGROUND

PMID: 21522061 (View on PubMed)

Other Identifiers

2013/00724

Identifier Type: -

Identifier Source: org_study_id