FIRMAGON® Intensive Drug Monitoring

NCT ID: NCT05181800

Last Updated: 2024-09-27

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1454 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-08-20

Study Completion Date

2022-12-31

Brief Summary

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To evaluate the safety profile of FIRMAGON® (to fulfill the regulatory authority's requirement of Intensive Drug Monitoring in Chinese participants with prostate cancer need androgen deprivation therapy \[ADT\] treated with FIRMAGON®).

Study Design

This study is a multi-center, single-arm, non-interventional, prospective study among Chinese participants with prostate cancer in need of ADT, receiving treatment with FIRMAGON®. This program provided the minimum 6 doses and maximum 12 doses of FIRMAGON® to enrolled participants during one-year follow-up. Participants who met the inclusion criteria would or were accepting at least 6 self-financed doses of treatment in a hospital. Participants should return to the hospital for medical assessment every three months. The prescription of 6 (3 doses × 2 times) self-financed doses will be given by doctors after assessment, and the direct-to-participant pharmacy will distribute FIRMAGON® to eligible participants (participants should bring the prescriptions and the last FIRMAGON® boxes to get other doses). All enrolled participants were followed up to collect safety information for one year from the 1st dose unless withdrawal of Informed Consent Form, discontinuation for 2 months, lost to follow-up, death, or termination due to other reasons, whichever came first.

Detailed Description

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Conditions

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Prostate Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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FIRMAGON® Cohort

Degarelix Cohort

Intervention Type OTHER

Non-interventional

Interventions

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Degarelix Cohort

Non-interventional

Intervention Type OTHER

Other Intervention Names

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FIRMAGON®

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with prostate cancer and in need of ADT
* Decision made to prescribe FIRMAGON® prior to enrollment
* Willingness and ability to provide written informed consent
* The participants are taking the marketed drug FIRMAGON®

Exclusion Criteria

* Not signed informed consent
* Any participants who are unsuitable to participate in this study because of any other reasons will not be qualified to participate in this study.
Minimum Eligible Age

18 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Ferring Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Global Clinical Compliance

Role: STUDY_DIRECTOR

Ferring Pharmaceuticals

Locations

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China Primary Healthcare Foundation

Beijing, , China

Site Status

Countries

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China

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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000351

Identifier Type: -

Identifier Source: org_study_id

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