Identification of Noninvasive Biomarkers for Neonates Undergoing Abdominal Surgery

NCT ID: NCT05181423

Last Updated: 2022-01-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-01

Study Completion Date

2024-12-31

Brief Summary

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To identify the potential serum and radiological biomarkers with regard to neonates undergoing abdominal surgery, and to further evaluate the prognostic value of these markers.

Detailed Description

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First, the investigators will collect serum biomarkers in neonate patients receiving abdominal surgery. Then the investigators will identify the characteristics and change of biomarkers expressed in neonate patients before and after abdominal surgery. The investigators will further evaluate the prognostic value of these markers for neonate patients receiving abdominal surgery.

Conditions

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Biomarkers Neonate

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Retrospective cohort

The internal cohort was retrospectively enrolled in West China Hospital, Sichuan University from June 2010 and December 2020. It is a training and internal validation cohort.

Biomarkers

Intervention Type OTHER

Different serum and radiological biomarkers neonates undergoing abdominal surgery.

Prospective cohort

The same inclusion/exclusion criteria were applied for the same center prospectively. It is a external validation cohort.

Biomarkers

Intervention Type OTHER

Different serum and radiological biomarkers neonates undergoing abdominal surgery.

Interventions

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Biomarkers

Different serum and radiological biomarkers neonates undergoing abdominal surgery.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age up to 18 years old
* With written informed consent

Exclusion Criteria

* Clinical data missing
* Without written informed consent
Minimum Eligible Age

0 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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West China Hospital

OTHER

Sponsor Role lead

Responsible Party

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Yuhan Yang

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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West China Hospital, Sichuan University

Chengdu, Sichuan, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Yuhan Yang, MD

Role: CONTACT

8613258389785

Facility Contacts

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Yuhan Yang, MD

Role: primary

8613258389785

Other Identifiers

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HX-2021657

Identifier Type: -

Identifier Source: org_study_id

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