ECMELLA vs. ECMO on 30-day Mortality

NCT ID: NCT05175898

Last Updated: 2022-01-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-02-28

Study Completion Date

2022-11-30

Brief Summary

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This international, multicenter cohort study aims to investigate outcomes after treatment with extracorporeal cardiopulmonary resuscitation (eCPR) during cardiac arrest.

Detailed Description

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Left ventricular unloading with Impella® micro-axial pump has been shown to improve survival in patients with cardiogenic shock treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). This study aims to investigate whether treatment with VA-ECMO and Impella ® (so called "ECMELLA") during extracorporeal cardiopulmonary resuscitation is associated with improved outcomes.

Conditions

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Cardiac Arrest Cardiopulmonary Arrest Extracorporeal Membrane Oxygenation Complication Cardiogenic Shock Acute Myocardial Infarction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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VA-ECMO

Patients who were treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) during cardiac arrest.

VA-ECMO

Intervention Type DEVICE

Treatment with veno-arterial extracorporeal membrane oxygenation

ECMELLA

Patients who were treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) and Impella® micro-axial pump.

ECMELLA

Intervention Type DEVICE

Treatment with veno-arterial extracorporeal membrane oxygenation plus Impella® micro-axial pump.

Interventions

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VA-ECMO

Treatment with veno-arterial extracorporeal membrane oxygenation

Intervention Type DEVICE

ECMELLA

Treatment with veno-arterial extracorporeal membrane oxygenation plus Impella® micro-axial pump.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult patients
* Cardiac arrest
* Treatment with veno-arterial extracorporeal membrane oxygenation (VA-ECMO) or "ECMELLA" (that is VA-ECMO plus left ventricular Impella® micro-axial pump)

Exclusion Criteria

* Non-adult patients
* No treatment with VA-ECMO or "ECMELLA"
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Carsten Skurk

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Carsten Skurk, MD

Role: PRINCIPAL_INVESTIGATOR

Charite University

Tharusan Thevathasan, MD

Role: PRINCIPAL_INVESTIGATOR

Charite University

Locations

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Charité - Universitätsmedizin Berlin

Berlin, , Germany

Site Status

Countries

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Germany

Other Identifiers

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ECMELLA vs. ECMO

Identifier Type: -

Identifier Source: org_study_id

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