The Prognostic Value of Serum Biomarkers in Ewing's Sarcoma

NCT ID: NCT05100368

Last Updated: 2023-07-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-04-02

Study Completion Date

2021-07-01

Brief Summary

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Extraction of laboratory data from blood tests prior to surgical and chemotherapy and other histological, clinical and instrumental data related to the patient's history from the digitized medical Digitized medical records and analysis of the same. The medical records of 1000 patients from January 1, 2000, until December 31, 2020

Detailed Description

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Conditions

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Sarcoma, Ewing

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients

Patients with Ewing's Sarcoma and osteosarcoma with established diagnosis

patients

Intervention Type OTHER

Patients with Ewing's Sarcoma and osteosarcoma with established diagnosis

Interventions

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patients

Patients with Ewing's Sarcoma and osteosarcoma with established diagnosis

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with Ewing's Sarcoma and osteosarcoma with established diagnosis;
* Patients with age ≥ 2 years;
* Minimum follow-up duration of 2 years;
* Medical records, complete blood work and instrumental examinations; Regular follow-up.

Exclusion Criteria

* Patients with Ewing's sarcoma or osteosarcoma who have received medical treatment (surgery radiotherapy or chemotherapy) in other institutions prior to admission to the Rizzoli Orthopaedic Institute.
Minimum Eligible Age

2 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituto Ortopedico Rizzoli

OTHER

Sponsor Role lead

Responsible Party

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Costantino Errani

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Istituto Ortopedico Rizzoli

Bologna, , Italy

Site Status

Countries

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Italy

References

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Nakamura T, Grimer RJ, Gaston CL, Watanuki M, Sudo A, Jeys L. The prognostic value of the serum level of C-reactive protein for the survival of patients with a primary sarcoma of bone. Bone Joint J. 2013 Mar;95-B(3):411-8. doi: 10.1302/0301-620X.95B3.30344.

Reference Type RESULT
PMID: 23450030 (View on PubMed)

Li YJ, Yang X, Zhang WB, Yi C, Wang F, Li P. Clinical implications of six inflammatory biomarkers as prognostic indicators in Ewing sarcoma. Cancer Manag Res. 2017 Sep 28;9:443-451. doi: 10.2147/CMAR.S146827. eCollection 2017.

Reference Type RESULT
PMID: 29033609 (View on PubMed)

Aggerholm-Pedersen N, Maretty-Kongstad K, Keller J, Baerentzen S, Safwat A. The Prognostic Value of Serum Biomarkers in Localized Bone Sarcoma. Transl Oncol. 2016 Aug;9(4):322-8. doi: 10.1016/j.tranon.2016.05.006.

Reference Type RESULT
PMID: 27567955 (View on PubMed)

Other Identifiers

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PROSARC

Identifier Type: -

Identifier Source: org_study_id

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