A First in Human Clinical Trial to Evaluate the Safety and Effectiveness of the STREAMLINE SURGICAL SYSTEM in Patients With Open-Angle Glaucoma

NCT ID: NCT05089474

Last Updated: 2023-10-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-08

Study Completion Date

2023-04-20

Brief Summary

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A prospective, nonrandomized, open label study to evaluate the safety and IOP lowering effectiveness of the Streamline Surgical System, in patients with mild-to-moderate open angle glaucoma undergoing cataract surgery.

Detailed Description

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A prospective, nonrandomized, open label study to evaluate the safety and IOP lowering effectiveness of the Streamline Surgical System, a viscoelastic delivery device, in patients with mild-to-moderate open angle glaucoma undergoing cataract surgery. This is a 12 month study conducted outside the US. Approximately 60 subjects will be enrolled.

Conditions

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Open Angle Glaucoma

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Prospective, non-randomized, open label
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Streamline

Streamline Surgical System

Group Type EXPERIMENTAL

Streamline Surgical System

Intervention Type DEVICE

The Streamline System is a device that delivers viscoelastic into Schlemm's Canal.

Interventions

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Streamline Surgical System

The Streamline System is a device that delivers viscoelastic into Schlemm's Canal.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Able to understand and execute written informed consent
2. Males or female subjects at least 22 years of age.
3. Subjects qualifying for cataract surgery
4. Subjects diagnosed with mild to moderate open-angle glaucoma in at least one eye currently treated with 1-3 topical IOP-lowering medications
5. Subjects with diagnosis of open-angle glaucoma in at least one eye with an unmedicated IOP of 21-36 mmHg

Exclusion Criteria

1. Women of child-bearing potential
2. Modified Shaffer angle grade \< 2
3. Patients with severe or advanced glaucoma
4. Intraocular surgery within the last 6 months or laser surgery within the last 3 months
5. BCVA worse than 20/80 in either eye
6. Patients with a previous peripheral iridotomy.
7. Ocular infection or inflammation within the last 6 months.
8. Any medication that would be contraindicated for a glaucoma surgical procedure.
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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New World Medical, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Clinica 20/20

San José, CR, Costa Rica

Site Status

Centro Laser

Santo Domingo, DR, Dominican Republic

Site Status

Clinica Laser y Ultrasonido Ocular de Puebla

Puebla City, , Mexico

Site Status

Countries

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Costa Rica Dominican Republic Mexico

Other Identifiers

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DF6-CL-20-01

Identifier Type: -

Identifier Source: org_study_id

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