PICO- Single-use Negative Pressure Wound Therapy System

NCT ID: NCT05064696

Last Updated: 2023-09-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-08-25

Study Completion Date

2025-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To compare the rate of wound complications with the PICO dressing versus a standard nonstick gauze dressing in patients undergoing anterior total ankle arthroplasty.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Participating subjects will be randomized to one of the study groups: Group 1 (Control group) or Group 2 (Treatment group). If randomized to Group 1- after surgery, the doctor will apply the standard non-stick gauze dressing to the wound. If randomized to Group 2- after surgery, the doctor will apply the PICO dressing to the wound.

The goal of the study is to measure the rate of wound complications based on wound assessment, patient-reported outcomes surveys, as well as peri- and post-operative data.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Total Ankle Arthroplasty

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group 1 (Control group)

Surgical wound will be covered with the standard non-stick gauze dressing.

Group Type ACTIVE_COMPARATOR

Non-stick gauze dressing

Intervention Type OTHER

Group 1 (Control group): surgical site will be dressed with a standard non-stick gauze dressing

Group 2 (Treatment group)

Surgical wound will be covered with the PICO dressing.

Group Type EXPERIMENTAL

PICO dressing

Intervention Type DEVICE

Group 2 (Treatment group): surgical site will be dressed with PICO dressing

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Non-stick gauze dressing

Group 1 (Control group): surgical site will be dressed with a standard non-stick gauze dressing

Intervention Type OTHER

PICO dressing

Group 2 (Treatment group): surgical site will be dressed with PICO dressing

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patient ≥18 years old
* Subjects undergoing total ankle arthroplasty or uncomplicated revision total ankle arthroplasty
* Subjects able to provide informed consent
* Subjects who are able to understand and comply with study visit schedule and procedures

Exclusion Criteria

* History of previous deep infection or history of wound complication necessitating plastic surgery intervention
* Allergy to products used in the study
* Pregnant and breastfeeding women due to anesthesia risks
* Subjects with a known history of poor compliance with medical treatment
* Subjects who decline participation in this research study
* Prisoners
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Smith & Nephew, Inc.

INDUSTRY

Sponsor Role collaborator

Walter C Hembree

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Walter C Hembree

MD

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Walter C Hembree, MD

Role: PRINCIPAL_INVESTIGATOR

MedStar Health

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Amy Loveland

Baltimore, Maryland, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Amy Loveland

Role: CONTACT

301-560-2937

Crisanto Macaraeg

Role: CONTACT

410-261-8218

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Amy Loveland

Role: primary

301-560-2937

Crisanto Macaraeg

Role: backup

410-261-8218

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

STUDY00003790

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Early Mobilization After Achilles Tendon Rupture
NCT02318472 ACTIVE_NOT_RECRUITING NA