Impact of COVID19 on Asthma Patients in Spain

NCT ID: NCT05064501

Last Updated: 2025-11-18

Basic Information

• Recruitment Status: WITHDRAWN
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-02-01
• Study Completion Date: 2024-06-01

Brief Summary

This research project aims to investigate the impact of COVID-19 on asthmatic patients, particularly focusing on whether the viral infection exacerbates asthma or affects control and lung function in the short to medium term. The study plans to collect and compare data from two groups of asthmatic individuals - those who have experienced a SARS-CoV-2 infection requiring emergency consultation or hospitalization and a matched control group without such infection. Both groups will be followed for one year, with lung function tests conducted at six months and monitoring of exacerbations and changes in Asthma Control Test (ACT) throughout the year. The objective is to enhance understanding of how COVID-19 affects asthmatic patients, leading to improved recommendations, preventive measures, and treatment adjustments based on the study's findings.

Detailed Description

The COVID19 pandemic is having an immeasurable impact on the economy and on morbidity and mortality. Knowledge and scientific evidence about this disease is advancing rapidly, but it is not yet known whether asthmatic patients suffering from COVID19 have an exacerbation of asthma, or whether this viral infection has an impact on control and lung function in the short to medium term.

The aim of this study is to define the changes that occur in these two parameters in asthmatic patients suffering from COVID19. To this end, asthmatic patients who have suffered a SARS-CoV-2 infection and who have required an emergency consultation or hospitalisation will be collected in a pneumology consultation and matched by age, sex and severity of asthma with a group that has not suffered the same. Both will be followed for one year, and lung function will be tested at six months and exacerbations and changes in ACT during the following year.

These data are intended to improve the available knowledge on the impact of IDVC19 on asthma patients with a view to making appropriate recommendations, prevention and treatment adjustments in line with the results obtained.

Conditions

Asthma; Covid19

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: PROSPECTIVE

Study Groups

Asthma and COVID19 infection

Asthma and COVID19 infection

spirometry

Intervention Type: DIAGNOSTIC_TEST

Lung function test: pre and post bronchodilator spirometry

Asthma control test

Intervention Type: OTHER

Asthma control test

Asthma without COVID19 infection

Asthma and COVID19 infection

spirometry

Intervention Type: DIAGNOSTIC_TEST

Lung function test: pre and post bronchodilator spirometry

Asthma control test

Intervention Type: OTHER

Asthma control test

Interventions

spirometry

Lung function test: pre and post bronchodilator spirometry

Intervention Type: DIAGNOSTIC_TEST

Asthma control test

Asthma control test

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• 12 -80 years
• Asthma diagnosis according to guidelines
• Follow up on asthma clinics in one of the participant hospitals

Exclusion Criteria

• Other severe respiratory condition independent of asthma

• Minimum Eligible Age: 12 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Sociedad Española de Neumología y Cirugía Torácica

OTHER

Sponsor Role: collaborator

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

elena Curto, PhD

Role: PRINCIPAL_INVESTIGATOR

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

Locations

Hospital de la Santa Creu i Sant Pau. Carrer Mas Casanovas 90.

Barcelona, , Spain

Hospital de la Santa Creu i Sant Pau

Barcelona, , Spain

Countries

Spain

Other Identifiers

IIBSP-COV-2020-129

Identifier Type: -

Identifier Source: org_study_id