How Does the Clinical and Paraclinical Efficacy of an Oral Appliance Evolved According to Propulsion: Control With Each mm of Advancement

NCT ID: NCT05056766

Last Updated: 2025-09-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-01

Study Completion Date

2022-09-01

Brief Summary

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The OAMMM study is a mono-centrer , non interventional, prospective study, carried out in CH Valence

Oral Appliance is indicated for first line moderate sleep Apnea Syndrome or severe sleep Apnea Syndrome after failure of positive airway pressure (CPAP).

Clinical impact of each mm advancement of Oral Appliance is imperfectly assessed.

The study aim to assess clinical and paraclinical efficacy of an oral Appliance on each mm of advancement.

Detailed Description

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Oral appliance will be delivered with a propulsion at 50% of the maximum advance and the investigator will titrate the advance according to the usual method

Polygraphy and clinical effectiveness of the Oral appliance will be evaluate

Conditions

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Sleep Apnea Syndromes Sleep Apnea, Obstructive Respiratory Tract Diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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single group assignement

questionnaires: Epworth Sleepiness Scale; Pichot fatigue questionnaire.

Intervention Type BEHAVIORAL

Each patient will undergo 3 to 7 polygraphy recordings according usual practice of titration At the same time, Self-questionnaires will be conducted by the patient in order to evaluate Oral appliance efficacy.

Optimal titration of oral appliance will be done according subjectives parameters. (sleepeness Reduction and fatigue Reduction).

Neither the investigator nor the patient will know the polygraphy results (apnea-hypopnea index)

Interventions

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questionnaires: Epworth Sleepiness Scale; Pichot fatigue questionnaire.

Each patient will undergo 3 to 7 polygraphy recordings according usual practice of titration At the same time, Self-questionnaires will be conducted by the patient in order to evaluate Oral appliance efficacy.

Optimal titration of oral appliance will be done according subjectives parameters. (sleepeness Reduction and fatigue Reduction).

Neither the investigator nor the patient will know the polygraphy results (apnea-hypopnea index)

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years old
* Moderate sleep apnea diagnosis with clinical signs
* Severe sleep apnea with failure continuous positive airway pressure( CPAP)

Exclusion Criteria

* previous sleep apnea treatment for Moderate sleep apnea
* refusal to participate in research
* Patient under guardianship, deprived of liberty, safeguard of justice
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ResMed

INDUSTRY

Sponsor Role collaborator

Centre Hospitalier de Valence

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Guillaume BUIRET, MD

Role: PRINCIPAL_INVESTIGATOR

CH VALENCE

Locations

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CH Valence

Valence, , France

Site Status

Countries

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France

Other Identifiers

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RIPH-CHV-03

Identifier Type: -

Identifier Source: org_study_id

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