Web-based Rehab After Acute Vertigo

NCT ID: NCT05056324

Last Updated: 2025-03-30

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 184 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-10-01
• Study Completion Date: 2025-03-12

Brief Summary

Acute onset vertigo is common and entails much suffering with persisting symptoms at 3 months after onset in up to half of those afflicted. Vestibular rehabilitation to aid recovery is not readily available. The purpose of this study is to investigate the effects on vertigo symptoms of a 6-week online vestibular rehabilitation tool compared with standard care (written instructions leaflet) after acute onset vertigo.

Conditions

Acute Vestibular Syndrome

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Intervention group

Group Type: EXPERIMENTAL

Online vestibular rehabilitation tool

Intervention Type: DEVICE

For those randomized to the intervention group, a 6 weeks duration vestibular rehabilitation will be delivered using an online tool (YrselTräning)

Control group

Group Type: ACTIVE_COMPARATOR

Standard care (written instructions leaflet)

Intervention Type: OTHER

For those randomized to the control group, a 6 weeks duration standard vestibular rehabilitation will be delivered using a written instructions leaflet

Interventions

Online vestibular rehabilitation tool

For those randomized to the intervention group, a 6 weeks duration vestibular rehabilitation will be delivered using an online tool (YrselTräning)

Intervention Type: DEVICE

Standard care (written instructions leaflet)

For those randomized to the control group, a 6 weeks duration standard vestibular rehabilitation will be delivered using a written instructions leaflet

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• ≥18 years old; and
• The subject has given written consent to participate in the study; and
• New acute onset dizziness or vertigo since ≥24 hours with pathological spontaneous or gaze-evoked nystagmus (i.e. an acute vestibular syndrome, AVS). The nystagmus as described above must be present at investigation between 24 hours and 7 days from onset, spontaneously, gaze-evoked or head-shake evoked and documented; and
• Screening and inclusion within 7 days of onset of continuous symptoms; and
• Symptomatic at inclusion

Exclusion Criteria

• Pre-existing vestibular disease or neurological disease anticipated to affect the ability to participate in the study or the effect of the intervention. N.B: Recurring AVS with no set diagnosis before inclusion is accepted, as is past transient neurological diseases such as TIA or migraine; or
• Inability to use the online rehabilitation tool, e.g. due to not having access to a computer, tablet or smartphone, not having access to the internet or lacking in experience with such tools; or
• Mental inability, reluctance or language difficulties that result in difficulty understanding the meaning of study participation; or
• Medical and/or physical contraindications to making the required head movements (e.g. vertebral dissection) or otherwise participating in the training and testing exercises or data collection; or
• Medication or other substance intake which can affect the ability to participate in the study or the reliability of the measurement methods. These medications include regular use of: Anticonvulsants, antiemetics/motion sickness medications, benzodiazepines, neuroleptics. Transient corticosteroid and/or antiemetic treatment related to the current vertigo is accepted.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Umeå

OTHER

Sponsor Role: collaborator

Sundsvall Hospital

OTHER

Sponsor Role: collaborator

Sahlgrenska University Hospital

OTHER

Sponsor Role: collaborator

Västernorrland County Council, Sweden

OTHER_GOV

Sponsor Role: collaborator

Södra Älvsborg Hospital

OTHER

Sponsor Role: collaborator

Karolinska University Hospital

OTHER

Sponsor Role: collaborator

University Hospital, Linkoeping

OTHER

Sponsor Role: collaborator

Sunderby Hospital

OTHER

Sponsor Role: collaborator

Capio Sankt Görans Hospital

OTHER

Sponsor Role: collaborator

Umeå University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Jonatan Salzer, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Umeå University

Locations

Södra Älvsborg Hospital

Borås, , Sweden

Sahlgrenska University Hospital

Gothenburg, , Sweden

University Hospital Linköping

Linköping, , Sweden

Sollefteå Hospital

Sollefteå, , Sweden

Sunderby Hospital

Södra Sunderbyn, , Sweden

Capio Sankt Görans Hospital

Stockholm, , Sweden

Karolinska University Hospital

Stockholm, , Sweden

Sundsvall Hospital

Sundsvall, , Sweden

University Hospital Umeå

Umeå, , Sweden

Countries

Sweden

References

Surano S, Faergemann E, Granasen G, Salzer J. The reliability and validity of the Swedish translation of the Vertigo Symptom Scale - short form in a cohort with acute vestibular syndrome. Ann Med. 2025 Dec;57(1):2457517. doi: 10.1080/07853890.2025.2457517. Epub 2025 Feb 10.

Reference Type: BACKGROUND

PMID: 39928092 (View on PubMed)

Surano S, Grip H, Ohberg F, Karlsson M, Faergemann E, Bjurman M, Davidsson H, Ledin T, Lindell E, Mathe J, Tjernstrom F, Tomanovic T, Granasen G, Salzer J. Internet-based vestibular rehabilitation versus standard care after acute onset vertigo: a study protocol for a randomized controlled trial. Trials. 2022 Jun 16;23(1):496. doi: 10.1186/s13063-022-06460-0.

Reference Type: BACKGROUND

PMID: 35710448 (View on PubMed)

Other Identifiers

CIV-21-05-036744

Identifier Type: OTHER

Identifier Source: secondary_id

Web-based vertigo rehab

Identifier Type: -

Identifier Source: org_study_id