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Interactive Rehabilitation for Adults With Unilateral Vestibular Weakness

NCT ID: NCT04875013

Last Updated: 2022-12-20

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-10

Study Completion Date

2021-10-31

Brief Summary

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People that have difficulty with balance, such as those with damage to their inner ear, have a higher risk of falling, which may lead to anxiety and reduced quality of life. Some individuals that have lost part of their sense of balance can learn to compensate using information from their vision, their sense of where their limbs are in space, and from other balance organs that are still intact. Our study aims to determine if virtual reality used together with information from footplate sensors can be used to train people with balance problems to compensate for their inner ear deficits.

Detailed Description

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Conditions

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Dizziness Equilibrium; Disorder, Labyrinth Inner Ear Injury

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Longitudinal cohort; single group assignment; interventional
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Vestibular rehabilitation with dynamic posturography

12 sessions, twice per week, of rehabilitation exercises last about 20 minutes, using CDP and interactive visual feedback

Group Type EXPERIMENTAL

Vestibular rehabilitation with dynamic posturography

Intervention Type DEVICE

Rehabilitation exercises guided by an interactive display and measured by a footplate sensor

Interventions

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Vestibular rehabilitation with dynamic posturography

Rehabilitation exercises guided by an interactive display and measured by a footplate sensor

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adult Age 18-80
* Unilateral vestibular weakness confirmed one or more of:

* Videonystagmography
* VEMP
* Or unilateral vestibular weakness idiopathic, not yet diagnosed (NYD)
* Persistent imbalance following diagnosis of resolved benign paroxysmal positional vertigo (BPPV)
* Symptomatic
* Long-standing/persistent symptoms greater than one year

Exclusion Criteria

* Orthopedic deficit (eg. lower body joint dysfunction or lower joint replacement)
* Neurological deficit or proprioception deficit
* Diabetes
* Poor vision or blindness
* Fluctuating vestibular symptoms, or condition known to fluctuate eg. Menière's disease, perilymphatic fistula (PLF) or superior canal deshicsence (SDCS)
* Active benign paroxysmal positional vertigo (BPPV)
* Undergoing treatment which may affect balance or ability to stand
* Cognitive impairment that prevents understanding and responding to instructions required to complete the study
* Inability to provide informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Eytan A. David

OTHER

Sponsor Role lead

Responsible Party

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Eytan A. David

MD, FRCSC, Clinical Instructor, Dept. of Surgery

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Eytan David, MD

Role: PRINCIPAL_INVESTIGATOR

University of British Columbia

Locations

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Dr. EA David MD FRCSC

North Vancouver, British Columbia, Canada

Site Status

Countries

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Canada

References

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David EA, Shahnaz N. Posturographic sensory ratios provide evidence for neuroplasticity after computerized vestibular rehabilitation therapy in a single group interventional trial. J Neuroeng Rehabil. 2025 Apr 11;22(1):81. doi: 10.1186/s12984-025-01608-w.

Reference Type DERIVED
PMID: 40217271 (View on PubMed)

David EA, Shahnaz N, Wiseman I, David Y, Cochrane CL. Computerized Dynamic Posturography-Guided Vestibular Rehabilitation Improves Vestibular Sensory Ratios. Ear Nose Throat J. 2025 Mar 12:1455613251321978. doi: 10.1177/01455613251321978. Online ahead of print.

Reference Type DERIVED
PMID: 40072844 (View on PubMed)

David EA, Shahnaz N. Dynamic posturography after computerized vestibular retraining for stable unilateral vestibular deficits. Acta Otolaryngol. 2023 May;143(5):396-401. doi: 10.1080/00016489.2023.2208615. Epub 2023 May 12.

Reference Type DERIVED
PMID: 37173291 (View on PubMed)

David EA, Shahnaz N. Patient-Reported Disability After Computerized Posturographic Vestibular Retraining for Stable Unilateral Vestibular Deficit. JAMA Otolaryngol Head Neck Surg. 2022 May 1;148(5):426-433. doi: 10.1001/jamaoto.2022.0167.

Reference Type DERIVED
PMID: 35357406 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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H20-04045

Identifier Type: -

Identifier Source: org_study_id