Therapeutic Effects of Topical Herbal Medicine -Rhubarb Ointment on Rosacea

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-08-04

Study Completion Date

2024-08-04

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The aim of this study is to investigate the effects of topical herbal medicine in the patients with rosacea.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Healing Effect of a Two-Herb Recipe on Foot Ulcer in Chinese Patients With Type 2 Diabetes

NCT01389362

Diabetic Foot Ulcer

COMPLETED PHASE2/PHASE3

Chinese Herbal Medicine for Psoriasis Vulgaris: a Real World Study

NCT03942185

Psoriasis

UNKNOWN PHASE2

Effect of Roselle-based Drink on Blood Pressure and Skin

NCT05084443

Other Skin and Subcutaneous Infections

COMPLETED NA

The Influence of Chinese Medicine on Metabolomics in Menopausal or Postpartum Women

NCT01264068

Menopausal Women

UNKNOWN PHASE3

Investigation on the Epidemic Prevention Effect of Using Chinese Medicine During the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Outbreak.

NCT05236309

COVID-19 Pandemic

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Rosacea is a chronic inflammatory disorder which affects the cheek, nose, chin, forehead and eyes. It is typically characterized by cutaneous signs such as flushing, erythema, telangiectasia, papules, and pustules in the face. The pathogenic mechanism of rosacea is unknown, and there is no cure for rosacea. The therapeutic approaches include oral medicine, topical medicine and surgical interventions depending on the different subtypes of rosacea. The recent study demonstrates that combination therapy may be more effectively improved the symptoms of rosacea. Dian dao san is a topical herbal compound for reducing the features as flushing, erythema, papules, and pustules for years. The investigators hypothesize that dian dao san can be more beneficial in treating the patients with rosacea and improving the quality of life.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Rosacea Chinese Herbal Medicine

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

group A (dian dao san group)

Herbal medicine (dian dao san) will be applied to the lesions of rosacea twice a day. Subject will receive persistent treatment for 6 weeks.

Group Type ACTIVE_COMPARATOR

dian dao san

Intervention Type DRUG

dian dao san and placebo will be used in the rosacea lesions twice a day for 6 weeks

group B( topical medicine without therapeutic effects)

Placebo (topical medicine without therapeutic effects) will be applied to the lesions of rosacea twice a day. Subject will receive persistent treatment for 6 weeks.

Group Type PLACEBO_COMPARATOR

dian dao san

Intervention Type DRUG

dian dao san and placebo will be used in the rosacea lesions twice a day for 6 weeks

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

dian dao san

dian dao san and placebo will be used in the rosacea lesions twice a day for 6 weeks

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Willing to sign inform consent
* Aged above 20 years old with rosacea
* No treatment for rosacea within 2 weeks

Exclusion Criteria

* With malignant lesion in the rosacea lesion
* Rosacea lesion with high risk of infection
* Allergy to Chinese herbal medicine patch or ointment
* Pregnancy

Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No