Evaluation of Spine Posture, Trunk Position Sense and Gait in Axial Spondyloarthritis Patients

NCT ID: NCT05038189

Last Updated: 2021-09-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

75 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-15

Study Completion Date

2022-03-31

Brief Summary

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Axial Spondyloarthritis (Ax-SpA) are chronic systemic inflammatory rheumatological diseases characterized by axial skeletal involvement and enthesitis. Sacroiliitis is the most prominent sign of the disease. The International Society for the Evaluation of Spondyloarthritis created a new classification for Ax-SpA in 2009. According to this classification, Ax-SpA; It is divided into two groups as ankylosing spondylitis (AS) and non-radiographic axial spondyloarthritis (nr-axSpA).

With the emergence of the term nr-axSpA, studies have begun to compare AS and nr-axSpA in terms of genetic, epidemiological and clinical features, treatment needs and response to treatment.However, more studies are needed to better understand the clinical features and symptoms of nr-axSpA patients.

The aim of this study was to determine the clinical features of patients with nr-axSpA and AS; To evaluate spine posture, trunk position sense and gait parameters, and also to compare these results with healthy individuals.

Detailed Description

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There are no studies comparing spine posture, trunk position sense and gait parameters in patients with nr-axSpA and AS. It is important to determine the changes that occur in nr-axSpA patients in the early period. At the same time, taking the necessary precautions and following these patients with the rehabilitation process can ensure that the radiographic development is delayed or not at all in the future.

Hypotheses:

H1: Trunk position sense is different from each other in individuals with Nr-axSpA and AS.

H2: Spatio-temporal features of gait are different in individuals with Nr-axSpA and AS.

H3: Plantar pressure distribution is different in individuals with Nr-axSpA and AS.

The Location of the Research: The research is carried out in Konya Necmettin Erbakan University Meram Faculty of Medicine, Rheumatology Department. After obtaining the permission of the ethics committee, official permission was obtained from Necmettin Erbakan University Meram Medical Faculty Hospital Chief Physician to conduct the study.

Conditions

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Non-radiographic Axial Spondyloarthritis Ankylosing Spondylitis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Ankylosing Spondylitis

Study group

Group Type EXPERIMENTAL

Gait parameters

Intervention Type DIAGNOSTIC_TEST

Trunk position sense as indicated by trunk reposition errors (TRE) and spine posture (thoracic and lumbar curvature) will be measured with a digital inclinometer. Gait analyses (cadence, stride length, swing phase duration, step duration and double stand duration) will be evaluated.

Non-radiographic Axial Spondyloarthritis

Study group

Group Type EXPERIMENTAL

Spine posture

Intervention Type DIAGNOSTIC_TEST

Trunk position sense as indicated by trunk reposition errors (TRE) and spine posture (thoracic and lumbar curvature) will be measured with a digital inclinometer. Gait analyses (cadence, stride length, swing phase duration, step duration and double stand duration) will be evaluated.

Healthy individuals

Control group

Group Type EXPERIMENTAL

Trunk position sense

Intervention Type DIAGNOSTIC_TEST

Trunk position sense as indicated by trunk reposition errors (TRE) and spine posture (thoracic and lumbar curvature) will be measured with a digital inclinometer. Gait analyses (cadence, stride length, swing phase duration, step duration and double stand duration) will be evaluated.

Interventions

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Gait parameters

Trunk position sense as indicated by trunk reposition errors (TRE) and spine posture (thoracic and lumbar curvature) will be measured with a digital inclinometer. Gait analyses (cadence, stride length, swing phase duration, step duration and double stand duration) will be evaluated.

Intervention Type DIAGNOSTIC_TEST

Spine posture

Trunk position sense as indicated by trunk reposition errors (TRE) and spine posture (thoracic and lumbar curvature) will be measured with a digital inclinometer. Gait analyses (cadence, stride length, swing phase duration, step duration and double stand duration) will be evaluated.

Intervention Type DIAGNOSTIC_TEST

Trunk position sense

Trunk position sense as indicated by trunk reposition errors (TRE) and spine posture (thoracic and lumbar curvature) will be measured with a digital inclinometer. Gait analyses (cadence, stride length, swing phase duration, step duration and double stand duration) will be evaluated.

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Trunk position sense Spine posture Gait parameters Trunk position sense Gait parameters Spine posture

Eligibility Criteria

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Inclusion Criteria

For AS and nr-axSpA;

* Diagnosed with AS and nr-axSpA by a rheumatologist according to ASAS criteria,
* Diagnosed with AS and nr-axSpA at least two years ago,
* Volunteer to participate in the study,
* Individuals between the ages of 18-65 will be included in the study.

For Healthy volunteers;

* Volunteer to participate in the study,
* Individuals between the ages of 18-65 will be included in the study.

Exclusion Criteria

For AS and nr-axSpA;

* Having orthopedic problems in the lower extremity,
* Locomotor disorders (fractures and prostheses) and / or osteoporosis,
* Having a history of lower extremity and spine surgery,
* Having neurological and cognitive problems,
* Having vision and hearing problems,
* Regular exercise,
* Individuals with kyphosis above 50 degrees will be excluded from the study.

For Healthy volunteers;

* Having any musculoskeletal, neurological and rheumatological diseases,
* Having any condition (advanced respiratory or orthopedic problems, fracture, sprain or spine surgery) that will prevent the evaluation,
* Regular exercise,
* Individuals who do not agree to participate in the study will be excluded from the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hacettepe University

OTHER

Sponsor Role collaborator

Necmettin Erbakan University

OTHER

Sponsor Role lead

Responsible Party

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YASEMİN AKKUBAK

Research Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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ADEM KÜÇÜK, Dr.

Role: STUDY_CHAIR

Necmettin Erbakan University, Faculty of Medicine, Meram/KONYA/TURKEY

Locations

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Yasemin Akkubak

Konya, Meram, Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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YASEMİN AKKUBAK, Res. Asiss.

Role: CONTACT

+905514327535

TÜLİN DÜGER, Prof.

Role: CONTACT

+905324714440

Facility Contacts

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YASEMİN AKKUBAK, Res. Assist.

Role: primary

05514327535

ADEM KÜÇÜK, Dr.

Role: backup

05514327535

Other Identifiers

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PhD_Yakkubak

Identifier Type: -

Identifier Source: org_study_id

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