Medical Records Investigation of Whether Perioperative Dexmedetomidine Will Reduce the Duration of Mechanical Ventilation or Hospital Length of Stay in Patients Undergoing Minimally Invasive Cardiac Surgery

NCT ID: NCT05038111

Last Updated: 2021-09-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

81 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-11

Study Completion Date

2021-03-25

Brief Summary

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The concept of enhanced recovery after surgery (ERAS) is utilizing in multiple specialties widely. Early tracheal extubation is one of the components of ERAS that enhances postoperative recovery and reduces the length of stay in intensive care unit (ICU).Dexmedetomidine is a highly selective, shorter-acting α2-adrenergic receptor agonist that has both analgesic and sedativeeffects.It was associated with decreased mortality, time to extubation, and hospital length of stay in cardiac surgical patients according to previous studies.The purpose of this study was to investigate the effect of perioperative dexmedetomidine on patients undergoing minimally invasive cardiac surgery(MICS) who were early extubated after surgery.

Detailed Description

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Conditions

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Mechanical Ventilation Hospital Length of Stay Minimally Invasive Cardiac Surgery

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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Dex

Dexmedetomidine infusion during the perioperative period

Dexmedetomidine

Intervention Type DRUG

perioperative dexmedetomidine infusion

Non-Dex

Did not have dexmedetomidine infusion during the perioperative period

No interventions assigned to this group

Interventions

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Dexmedetomidine

perioperative dexmedetomidine infusion

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients undergone minimal invasive off-pump coronary artery bypass graft (CABG), valvular surgery or combined procedures at Far Eastern Memorial Hospital, New Taipei City, Taiwan between January 1, 2020 and August 31, 2020.
* Age above 20 y/o

Exclusion Criteria

* Emergency surgery
* Postoperative mechanical ventilation more than 6 hours
* Extubated in the operating room
Minimum Eligible Age

20 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Far Eastern Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tsung-Hua Yang, MD

Role: PRINCIPAL_INVESTIGATOR

Far Eastern Memorial Hospital

Locations

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Far Eastern Memorial Hospital

New Taipei City, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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110006-F

Identifier Type: -

Identifier Source: org_study_id

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