Efficacy and Safety of KBP-5074 in Uncontrolled Hypertension and Moderate or Severe Chronic Kidney Disease (CKD)

NCT ID: NCT04968184

Last Updated: 2025-09-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

652 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-05

Study Completion Date

2024-07-10

Brief Summary

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This Phase 3, randomized, Double-blind, placebo-controlled, 2-arm, parallel-group, multicenter study with randomized withdrawal will evaluate the efficacy, safety, and durability of KBP-5074 in adult participants who have stage 3b/4 chronic kidney disease (CKD) (estimated glomerular filtration rate \[eGFR\] calculated using the Chronic Kidney Disease Epidemiology Collaboration \[CKD-EPI\] formula \[eGFR {EPI}\] ≥15 to ≤44 mL/min/1.73 m\^2) and uncontrolled hypertension (systolic blood pressure (SBP) ≥140 and \<180 mm Hg and taking 2 or more antihypertensive medications.

Detailed Description

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Participants in this study will be recruited, screened, and enrolled at approximately 140 study sites globally.

The study will consist of the following periods:

1. Pretreatment Phase: This will include prescreening assessment and screening period of up to 4 weeks and 2-week Open-label placebo Run-In period.
2. A 24-week Double-blind Treatment Period (Randomization to Week 24) will include: An initial 12-week (Randomization to Week 12) and second 12-week (Week 12 to Week 24) treatment period and a second 12-week treatment period (Week 12 to Week 24), during both the periods study drug will be titrated.
3. A 24-week Open-label Treatment Period (Week 24 to Week 48) during which eligible participants will receive Open-label KBP-5074.
4. A 4-week Randomized Double-blind Withdrawal Period (Week 48 to Week 52) during which eligible participants will be randomized to continue their current KBP-5074 dose at the end of Open-label treatment or receive matching placebo for 4 weeks.
5. A 4-week post-treatment Follow-Up Period (Week 52 to Week 56).

During, 24-week Double-blind Treatment Period, 24-week Open-label Treatment Period, and at 4-week Randomized Double-blind Withdrawal Period, the background antihypertensive medications change may or may not be allowed.

At Double-blind Treatment Period, eligible participants will be randomly assigned in a 1:1 ratio to KBP-5074 0.25 mg or matching placebo once daily (QD).

At the Randomized Double-blind Withdrawal Period, participants who meet the randomized withdrawal criteria will be randomly assigned in a 1:1 ratio to continue their current KBP-5074 dose at the end of the Open-label Treatment Period or matching placebo QD.

Conditions

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Chronic Kidney Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors
All individuals directly involved in the conduct of the study, including participants, Investigators, site staff, clinical research organization (CRO) personnel, and Sponsor study personnel, will remain blinded to treatment assignments until all participants have completed the Week 56 end of study (EOS) Visit (Visit 17) and the database locked in preparation.

Study Groups

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Placebo

Open-label Placebo Run-In Period: All eligible participants will receive matching placebo, for approximately 2 weeks, during the Open-label placebo Run-In period.

Double-blind Treatment Period: All eligible participants will receive matching placebo, from week 2 thru week 24 during the Double-blind treatment Period

Open-label Treatment Period: All eligible participants will receive KBP-5074, from week 24 thru week 48 during the Open label Treatment Period

Randomized Double-blind Withdrawal Period: All eligible participants will be randomized to either continue their current KBP-5074 dose at the end of the Open-Label Treatment Period or receive matching placebo from week 48 thru week 52.

Follow up Period: All participants will discontinue matching placebo/KBP-5074 and be followed for safety until end of study visit from week 52 to week 56.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

Participants will orally receive placebo matching to KBP-5074 tablets QD.

KBP-5074

Open-label Placebo Run-In period: All eligible participants will receive matching placebo, for approximately 2 weeks during the Open-label placebo Run-In period.

Double-blind Treatment Period: All eligible participants will receive KBP-5074, from week 2 thru week 24 during the Double-blind Treatment Period

Open-label Treatment Period: All eligible participants will receive KBP-5074, from week 24 thru week 48 during the Open label Treatment Period

Randomized Double-blind Withdrawal Period: All eligible participants will be randomized to either continue their current KBP-5074 dose at the end of the Open-Label Treatment Period or receive matching placebo from week 48 thru week 52.

Follow up Period: All participants will discontinue matching placebo/KBP-5074 and be followed for safety until end of study visit from week 52 to week 56.

Group Type EXPERIMENTAL

KBP-5074

Intervention Type DRUG

Participants will orally receive KBP-5074 tablets, from 0.25 mg to a maximum dose of 0.5-mg QD.

Interventions

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Placebo

Participants will orally receive placebo matching to KBP-5074 tablets QD.

Intervention Type DRUG

KBP-5074

Participants will orally receive KBP-5074 tablets, from 0.25 mg to a maximum dose of 0.5-mg QD.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Body mass index (BMI) must be ≥19 to \<45 kg/m\^2 at the Screening Visit
* Participant must have uncontrolled hypertension defined as meeting both of the following criteria:

* The participant has a resting seated trough cuff SBP ≥140 mm Hg at the Screening Visit (Visit 1), and at the start (Visit 2) and end (Visit 3) of the Run-In Period
* The participant is taking 2 or more antihypertensive medications that have been titrated upward as tolerated to hypertension target doses per local SoC and have been stable (i.e., without any dose adjustments) from 4 weeks before the Screening Visit (Visit 1) through the end of the Run-In Period (Visit 3)
* The participant must have Stage 3b (eGFR \[EPI\] ≥30 and ≤44 mL/min/1.73 m\^2) or Stage 4 (eGFR \[EPI\] ≥15 and \<30 mL/min/1.73 m\^2) CKD.

Exclusion Criteria

* Participant has a resting seated trough cuff SBP ≥180 mm Hg at the Screening Visit (Visit 1) or at the start (Visit 2) or end (Visit 3) of the Run-In Period
* Participant has a serum potassium level \>4.8 mmol/L during the Screening or Run-In Periods
* Participant has had a serum potassium level \>5.6 mmol/L within 2 weeks before the Screening Visit (Visit 1)
* Participant has been hospitalized for hyperkalemia within the 3 months before the Randomization Visit (Visit 3)
* Participant was not compliant with taking placebo during the Run-in Period or participant was not compliant with background antihypertensive medications during the Run-in Period as assessed at the Randomization Visit (Visit 3)
* Participant has taken an mineralocorticoid receptor antagonist (MRA), a potassium-sparing diuretic, or chronic potassium supplements during the 4 weeks before the Screening Visit (Visit 1)
* Participant has taken potassium binders for the treatment of hyperkalemia during the 3 months before the Screening Visit (Visit 1)
* Participant has taken a strong cytochrome P450 (CYP) CYP3A4 inducer or strong CYP3A4 inhibitor during the 7 days before the Randomization Visit (Visit 3)
* Participant has taken a prohibited traditional Chinese medication during the 28 days prior to Screening Visit (Visit 1).
* Participant was administered any other investigational product within 4 weeks or 5 half-lives (whichever is longer) prior to the Screening Visit (Visit 1).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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KBP Biosciences

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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G & L Research, LLC

Foley, Alabama, United States

Site Status

Apogee Clinical Research, LLC

Huntsville, Alabama, United States

Site Status

Aventiv Research, Inc

Mesa, Arizona, United States

Site Status

National Heart Institute

Beverly Hills, California, United States

Site Status

Amicis Research Center (Valencia)

Granada Hills, California, United States

Site Status

Amicis Research Center

Granada Hills, California, United States

Site Status

Amicis Research Center

Lancaster, California, United States

Site Status

Renal Consultants Medical Group - Granada Hills

Northridge, California, United States

Site Status

United Clinical Research and Innovations

South Gate, California, United States

Site Status

Solano Kidney Care

Vacaville, California, United States

Site Status

Desert Cities Dialysis - Amethyst

Victorville, California, United States

Site Status

Kidney and Hypertension Center

Victorville, California, United States

Site Status

Davita Clinical Research-Hartford

Bloomfield, Connecticut, United States

Site Status

Synergy Healthcare

Bradenton, Florida, United States

Site Status

Homestead Associates in Research, Inc

Miami, Florida, United States

Site Status

Total Research Group

Miami, Florida, United States

Site Status

LCC Medical Research

Miami, Florida, United States

Site Status

Oceane 7 Medical&Research Center, Inc.

Miami, Florida, United States

Site Status

Allied Biomedical Research Institute

Miami, Florida, United States

Site Status

South Florida Research Phase I-Iv, Inc.

Miami, Florida, United States

Site Status

San Marcus Research Clinic, Inc.

Miami Lakes, Florida, United States

Site Status

Inpatient Research Clinic, LLC

Miami Lakes, Florida, United States

Site Status

New Generation Of Medical Research

Naples, Florida, United States

Site Status

Sarkis Clinical

Ocala, Florida, United States

Site Status

Omega Research Orlando, LLC

Orlando, Florida, United States

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Genesis Clinical Research

Tampa, Florida, United States

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Santos Research Center CORP

Tampa, Florida, United States

Site Status

Fides Clinical Research

Atlanta, Georgia, United States

Site Status

Southeastern Clinical Research Institute, LLC

Augusta, Georgia, United States

Site Status

Columbus Associates LLC

Columbus, Georgia, United States

Site Status

Central Georgia Kidney Specialists

Macon, Georgia, United States

Site Status

Clinical Investigation Specialists, Inc.

Gurney, Illinois, United States

Site Status

Massachusetts General Hospital (MGH) - Renal Associates Clinic

Boston, Massachusetts, United States

Site Status

InterMed Consultants

Edina, Minnesota, United States

Site Status

Healthcare Research Network

Hazelwood, Missouri, United States

Site Status

Clinical Research Consultants

Kansas City, Missouri, United States

Site Status

St. Louis Heart and Vascular, P.C. (SLHV) - Christian Hospital Office

St Louis, Missouri, United States

Site Status

Healor Primary Care /CCT Research

Las Vegas, Nevada, United States

Site Status

DaVita Clinical Research (Nevada)

Las Vegas, Nevada, United States

Site Status

NYC Health + Hospitals / Queens - Diabetes Center of Excellence

Jamaica, New York, United States

Site Status

Mattoo & Bhat Medical Associates, PC

Ridgewood, New York, United States

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Albert Einstein's College of Medicine

The Bronx, New York, United States

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Kidney Medical Associates, PLLC

The Bronx, New York, United States

Site Status

Mountain Kidney & Hypertension Associates (MKHA), P.A - Asheville

Asheville, North Carolina, United States

Site Status

Physicians East, PA

Greenville, North Carolina, United States

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Eastern Nephrology Associates - Jacksonville

Jacksonville, North Carolina, United States

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Eastern Nephrology Associates - New Bern

New Bern, North Carolina, United States

Site Status

North Carolina Nephrology P.A.

Raleigh, North Carolina, United States

Site Status

Brookview Hills Research Associates, LLC

Winston-Salem, North Carolina, United States

Site Status

Providence Health Partners-Center for Clinical Research

Dayton, Ohio, United States

Site Status

Columbia Nephrology Associates, PA

Columbia, South Carolina, United States

Site Status

Knoxville Kidney Center, PLLC

Knoxville, Tennessee, United States

Site Status

Gamma Clinical Research Institute

Austin, Texas, United States

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Davita Clinical Research El Paso

El Paso, Texas, United States

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Kidney Consultants of El Paso, P.A.

El Paso, Texas, United States

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DaVita Clinical Research Houston

Houston, Texas, United States

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Pioneer Research Solutions, Inc.

Houston, Texas, United States

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Clinical Advancement Center, PLLC

San Antonio, Texas, United States

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Urology San Antonio - North Central

San Antonio, Texas, United States

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DaVita Clinical Research

San Antonio, Texas, United States

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Kidney Specialists of North Houston, PLLC

The Woodlands, Texas, United States

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Davita Norfolk Square

Norfolk, Virginia, United States

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Dominion Medical Associates, Inc.

Richmond, Virginia, United States

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Clinical Investigation Specialists

Kenosha, Wisconsin, United States

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Milwaukee Nephrologists, SC (Rich)

Wauwatosa, Wisconsin, United States

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Renal Research

Gosford, New South Wales, Australia

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Royal Adelaide Hospital

Adelaide, South Australia, Australia

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Austin Hospital

Heidelberg, Victoria, Australia

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Clinical Center University of Sarajevo

Sarajevo, Kanton Sarajevo, Bosnia and Herzegovina

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Univerzitetski klinicki centar Republike Srpske - Internal Medicine, Nephrology

Banja Luka, Republika Srpska, Bosnia and Herzegovina

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The University Hospital Foca

Foča, Republika Srpska, Bosnia and Herzegovina

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General Hospital Gradiska

Gradiška, Republika Srpska, Bosnia and Herzegovina

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General hospital Trebinje - Gastroenterology

Trebinje, Republika Srpska, Bosnia and Herzegovina

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General Hospital Tesanj

Tešanj, Zeničko-dobojski Kanton, Bosnia and Herzegovina

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5 th MHAT

Sofia, Sofia-Grad, Bulgaria

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Medical Center Excelsior

Sofia, Sofia-Grad, Bulgaria

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UMHAT St. Ekaterina

Sofia, Sofia-Grad, Bulgaria

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Comac Medical Ltd

Sofia, Sofia-Grad, Bulgaria

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Mhat Dr.Tota Venkova

Gabrovo, , Bulgaria

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Medical Center Hera EOOD

Montana, , Bulgaria

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UMHAT Kaspela

Plovdiv, , Bulgaria

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Medical Center "Teodora"

Rousse, , Bulgaria

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DCC 22 - Sofia

Sofia, , Bulgaria

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Medical Center Hera EOOD

Sofia, , Bulgaria

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Medical Center ''Synexus Sofia'' EOOD

Sofia, , Bulgaria

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University Hospital of Active Treatment Prof. Stoyan Kirkovich

Stara Zagora, , Bulgaria

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MHAT"Sv.Anna-Varna"AD

Varna, , Bulgaria

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Dr. Stephen S. Chow Medicine Professional Corporation

Toronto, Ontario, Canada

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Clinical Research Solutions Incorporated

Waterloo, Ontario, Canada

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Beijing Chao-Yang Hospital, Capital Medical University

Beijing, Beijing Municipality, China

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Beijing An Zhen Hospital, Capital Medical University

Beijing, Beijing Municipality, China

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China-Japan Friendship Hospital

Beijing, Beijing Municipality, China

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Peking University First Hospital

Beijing, Beijing Municipality, China

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Beijing Hospital

Beijing, Beijing Municipality, China

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The First Affiliated Hospital of Fujian Medical University

Fuzhou, Fujian, China

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The First Affiliated Hospital of Xiamen University

Xiamen, Fujian, China

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Zhongshan Hospital Xiamen University

Xiamen, Fujian, China

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Guangdong Provincial People's Hospital

Guangzhou, Guangdong, China

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Guangzhou First People's Hospital - Nephrology

Guangzhou, Guangdong, China

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The Third Affiliated Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China

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The People's Hospital of Guangxi Zhuang Autonomous Region- Nephrology

Nanning, Guangxi, China

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The Affliated Hospital of Guizhou Medical University

Guiyang, Guizhou, China

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The Second Hospital of Hebei Medical University

Shijiazhuang, Hebei, China

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The First Affiliated Hospital of Zhengzhou University (East Compus)

Zhengzhou, Henan, China

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The Central Hospital of Wuhan

Wuhan, Hubei, China

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The Second Xiangya Hospital of Central South University

Changsha, Hunan, China

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The Third Xiangya Hospital of Central South University

Changsha, Hunan, China

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Jiangsu Province Hospital/ The First Affiliated Hospital with Nanjing Medical University

Nanjing, Jiangsu, China

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Wuxi People's Hospital

Wuxi, Jiangsu, China

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The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science and Technology

Baotou, Nei Mongol (mn), China

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General Hospital of Ningxia Medical University

Yinchuan, Ningxia, China

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The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, China

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Shandong Provincial Hospital

Jinan, Shandong, China

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Yantai Yuhuangding Hospital(Base Cpmpus)

Yantai, Shandong, China

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Shanghai General Hospital

Shanghai, Shanghai Municipality, China

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Sichuan Academy of Medical Sciences

Chengdu, Sichuan, China

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The Second Affiliated Hospital of Zhejiang University School of Medicine

Hangzhou, Zhejiang, China

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Zhejiang Hospital

Hangzhou, Zhejiang, China

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Zhejiang Provincial People's Hospital

Hangzhou, Zhejiang, China

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Jinhua Central Hospital

Jinhua, Zhejiang, China

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The First Affiliated Hospital of Wenzhou Medical University

Wenzhou, Zhejiang, China

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The Southwest Hospital of AMU

Chongqing, , China

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Shanghai Sixth People's Hospital

Shanghai, , China

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Tianjin Medical University General Hospital

Tianjin, , China

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University Hospital Centre Zagreb

Zagreb, City of Zagreb, Croatia

Site Status

Opca bolnica Vinkovci

Vinkovci, Osjecko-baranjska Županija, Croatia

Site Status

University Hospital Center Split

Split, , Croatia

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Nefrologie s.r.o.

Prague, Praha 4, Czechia

Site Status

Nemocnice Trebic, p.o.

Třebíč, Třebíč, Czechia

Site Status

IKEM

Prague, , Czechia

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Alaron s.r.o.

Prague, , Czechia

Site Status

LTD "High technology hospital MEDCENTER"

Batumi, Adjara, Georgia

Site Status

Ltd Marnecor

Marneuli, Kvemo Kartli, Georgia

Site Status

Ministry of Defence of Georgia LEPL Giorgi Abramishvili Military Hospital

Gori, Shida Kartli, Georgia

Site Status

JSC "Evex Hospitals'

Batumi, , Georgia

Site Status

Aleksandre Aladashvili Clinic LLC

Tbilisi, , Georgia

Site Status

LTD Israel-Georgian Medical Research Clinic Helsicore

Tbilisi, , Georgia

Site Status

"Pineo Medical Ecosystem"LTD

Tbilisi, , Georgia

Site Status

JSC German Clinic

Tbilisi, , Georgia

Site Status

National Center of Urology Named after Laur Managadze

Tbilisi, , Georgia

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Bokhua Memorial Cardiovascular Centre

Tbilisi, , Georgia

Site Status

Emergency Cardiology Center named by acad. G. Chapidze

Tbilisi, , Georgia

Site Status

J.S.C."K.Eristavi National Center of Experimental and Clinical Surgery"

Tbilisi, , Georgia

Site Status

Nephrologisches Zentrum Villingen-Schwenningen

Villingen-Schwenningen, Baden-Wurttemberg, Germany

Site Status

Diabeteszentrum DO

Dortmund, North Rhine-Westphalia, Germany

Site Status

DaVita Clinical Research Germany GmbH

Düsseldorf, North Rhine-Westphalia, Germany

Site Status

Universitätsklinikum Mainz

Mainz, Rhineland-Palatinate, Germany

Site Status

Charité- Universitätsmedizin Berlin

Berlin, , Germany

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Charité - Universitätsmedizin Berlin

Berlin, , Germany

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Medizinische Hochschule Hannover

Hanover, , Germany

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Universitätsklinikum Jena

Jena, , Germany

Site Status

Queen Mary Hospital - Medicine

Hong Kong, , Hong Kong

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Tung Wah Hospital

Hong Kong, , Hong Kong

Site Status

Coromed-Smo Kft.

Pécs, Baranya, Hungary

Site Status

IPR Hungary Kft.

Miskolc, Borsod-Abauj Zemplen county, Hungary

Site Status

Sonocor Egészségügyi Szolgáltató Kft.

Szeged, Csongrád megye, Hungary

Site Status

TaNa Med Kft

Mosonmagyaróvár, Győr-Moson-Sopron, Hungary

Site Status

BKS Research

Hatvan, Heves County, Hungary

Site Status

Kistarcsai Flor Ferenc Korhaz

Kistarcsa Hungary, Pest County, Hungary

Site Status

DRC Gyógyszervizsgáló Központ Kft.

Balatonfüred, Veszprém City, Hungary

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Semmelweis Egyetem

Budapest, , Hungary

Site Status

Jahn Ferenc Dél-Pesti Kórház és Rendelőintézet

Budapest, , Hungary

Site Status

Somogy Megyei Kaposi Mór Oktató Kórház

Kaposvár, , Hungary

Site Status

Rabin Medical Center

Petah Tikwa, Central District, Israel

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Nazareth Hospital EMMS

Nazareth, Northern District, Israel

Site Status

Dace Teterovska - Doctor's Practice

Ogre, Ogre, Latvia

Site Status

P.Stradina Clinical University Hospital

Riga, , Latvia

Site Status

Saules seimos medicinos centras

Kaunas, Kaunas County, Lithuania

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Hospital Raja Perempuan Zainab II

Kota Bharu, Kelantan, Malaysia

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Hospital Kuala Lumpur

Kuala Lumpur, Kuala Lumpur, Malaysia

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University Malaya Medical Centre

Kuala Lumpur, Kuala Lumpur, Malaysia

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Hospital Raja Permaisuri Bainun

Ipoh, Perak, Malaysia

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Hospital Seri Manjung

Seri Manjung, Perak, Malaysia

Site Status

NZOZ Euromedica Sp. z o.o.

Grudziądz, Kuyavian-Pomeranian Voivodeship, Poland

Site Status

Prywatny Gabinet Lekarski i Wizyty Lekarskie Jan Ruxer

Lodz, Lódzkie, Poland

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Synexus Polska Sp. z o.o.

Katowice, , Poland

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Synexus Polska Sp. z. o.o.

Lodz, , Poland

Site Status

SP ZOZ Centralny Szpital Kliniczny UM w Lodzi

Lodz, , Poland

Site Status

Samodzielny Publiczny Szpital Kliniczny nr 4 w Lublinie

Lublin, , Poland

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Synexus Polska Sp. z o.o.

Poznan, , Poland

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Synexus Polska Sp. z o.o.

Warsaw, , Poland

Site Status

WroMedica I. Bielicka, A. Strzalkowska s.c.

Wroclaw, , Poland

Site Status

Clinical Hospital Centre Zemun

Zemun, Belgrade, Serbia

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Clinical Centre Nis

Niš, Nišavski Okrug, Serbia

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Clinical Center Vojvodina

Novi Sad, Vojvodina, Serbia

Site Status

Military Medical Academy

Belgrade, , Serbia

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Zvezdara University Medical Center

Belgrade, , Serbia

Site Status

MSB General hospital - Clinical Research Center

Belgrade, , Serbia

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Clinical Center Kragujevac

Kragujevac, , Serbia

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Iatros International

Bloemfontein, Free State, South Africa

Site Status

Charlotte Maxeke Johannesburg Hospital

Soweto, Gauteng, South Africa

Site Status

Office of Gulam Hoosain Vally

Durban, KwaZulu-Natal, South Africa

Site Status

Tiervlei Trial Centre

Bellville, Cape Town, Western Cape, South Africa

Site Status

Dr J.M. Engelbrecht Trial Site

Somerset West, Western Cape, South Africa

Site Status

Chungnam National University Hospital - Nephrology

Daejeon, Daejeon Gwang'yeogsi [Taejon-Kwangyokshi], South Korea

Site Status

National Health Insurance Service Ilsan Hospital - Nephrology

Goyang-si, Gyeonggido [Kyonggi-do], South Korea

Site Status

Seoul National University Hospital - Nephrology

Jongno-gu, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea

Site Status

Gangnam Severance Hospital, Yonsei University Health System - Internal Medicine

Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea

Site Status

Samsung Medical Center - Nephrology

Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea

Site Status

The Catholic University of Korea, Seoul St. Mary's Hospital

Seoul, Seoul Teugbyeolsi [Seoul-T'ukpyolshi], South Korea

Site Status

Hospital público da Mariña

Burela de Cabo, Lugo, Spain

Site Status

Hospital Ribera Polusa

Burela de Cabo, Lugo, Spain

Site Status

Consorcio Hospital General Universitario de Valencia

Valencia, Valenciana, Comunidad, Spain

Site Status

FUNDACION PUIGVERT - Nephrology Department

Barcelona, , Spain

Site Status

Hospital del Mar

Barcelona, , Spain

Site Status

Hospital Quironsalud Barcelona

Barcelona, , Spain

Site Status

Hospital de La Santa Creu i Sant Pau

Barcelona, , Spain

Site Status

Hospital Universitario Virgen de las Nieves

Granada, , Spain

Site Status

Hospital Universitario Fundación Jiménez Díaz

Madrid, , Spain

Site Status

Hospital Universitario Y Politécnico La Fe

Valencia, , Spain

Site Status

Taichung Veterans General Hospital - Nephrology

Taichung, Taichung Municipality, Taiwan

Site Status

National Taiwan University Hospital - Nephrology

Taipei, Taipei Special Muncipality, Taiwan

Site Status

China Medical University Hospital - Nephrology - Taichung

Taichung, , Taiwan

Site Status

Taipei Medical University - Shuang Ho Hospital - Nephrology

Taipei, , Taiwan

Site Status

Chang Gung Medical Foundation - LinKou Chang Gung Memorial Hospital - Nephrology

Taoyuan District, , Taiwan

Site Status

Countries

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United States Australia Bosnia and Herzegovina Bulgaria Canada China Croatia Czechia Georgia Germany Hong Kong Hungary Israel Latvia Lithuania Malaysia Poland Serbia South Africa South Korea Spain Taiwan

Other Identifiers

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KBP5074-3-001

Identifier Type: -

Identifier Source: org_study_id

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