Trial Outcomes & Findings for Understanding Visual Confusion Using Stereoscopic Displays (NCT NCT04957745)

NCT ID: NCT04957745

Last Updated: 2023-07-10

Results Overview

(Total time the peripheral target in the visual confusion condition was visible) / (total viewing time (=1 min))

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

13 participants

Primary outcome timeframe

Approximately 1-2 sessions to finish total 6 trials, up to 2 hours for each session, any time within the 4month study period

Results posted on

2023-07-10

Participant Flow

13 participants were recruited and screened for eligibility and all of them met the inclusion criteria.

13 participants were recruited and screened for eligibility and all of them met the inclusion criteria.

Participant milestones

Participant milestones
Measure
Visual Confusion
Participants viewed peripheral targets in three different visual confusion conditions (three interventions): binocular visual confusion (unilateral opaque target), unilateral monocular visual confusion (unilateral see-through target), and bilateral monocular visual confusion (bilateral see-through target). Each intervention was presented twice in a randomized order, resulting in a total of six trials. During each trial, a peripheral target was presented in front of a forward-moving background for one minute. Participants were instructed to hold down the controller button while the target was visible and release it when a third or more of the target disappeared. After each trial, participants could take a brief break before the next trial in a different visual confusion condition was presented in a randomized order.
Overall Study
STARTED
13
Overall Study
COMPLETED
13
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Understanding Visual Confusion Using Stereoscopic Displays

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Visual Confusion
n=13 Participants
The study participants will respond to various visual confusion stimuli presented on a stereoscopic display designed to simulate binocular/monocular visual confusions Visual confusion: We will show peripheral target images on a background motion in a stereoscopic display. For the binocular visual confusion condition, the target peripheral image will be displayed on only one eye. For unilateral and bilateral monocular visual confusion conditions, the half-transparent peripheral image will be displayed on only one eye and both eyes, respectively.
Age, Continuous
30.46 years
STANDARD_DEVIATION 7.25 • n=5 Participants
Sex: Female, Male
Female
8 Participants
n=5 Participants
Sex: Female, Male
Male
5 Participants
n=5 Participants
Race/Ethnicity, Customized
White/Non-hispanic
5 Participants
n=5 Participants
Race/Ethnicity, Customized
Asian/Non-hispanic
8 Participants
n=5 Participants
Region of Enrollment
United States
13 participants
n=5 Participants
Visual acuity
19.38 Snellen fraction (20/X)
STANDARD_DEVIATION 4.21 • n=5 Participants
Stereo-acuity
27.7 arcseconds
STANDARD_DEVIATION 9.28 • n=5 Participants

PRIMARY outcome

Timeframe: Approximately 1-2 sessions to finish total 6 trials, up to 2 hours for each session, any time within the 4month study period

Population: Each subject observed two trials in each visual confusion condition. There were three visual confusion conditions, so each subject participated in 6 trials. Since 13 subjects participated, the total number of trials analyzed was 78 trials (6 \* 13). For each visual confusion condition, 26 trials were analyzed.

(Total time the peripheral target in the visual confusion condition was visible) / (total viewing time (=1 min))

Outcome measures

Outcome measures
Measure
Visual Confusion
n=78 Trials
Participants viewed peripheral targets in three different visual confusion conditions (three interventions) - Binocular visual confusion (unilateral opaque target), Unilateral monocular visual confusion (unilateral see-through target), and Bilateral monocular visual confusion (bilateral see-through target) - twice in a randomized order, resulting in a total of six trials. During each trial, the peripheral target in a different visual confusion in front of a forward-moving background was presented to the participant for 1 minute. Participants were instructed to hold down the controller button while the target was visible and release it when a third or more of the target disappeared. After each trial, participants could take a brief break (e.g., blinking eye) before the next trial in a different visual confusion condition was presented in a randomized order.
Percentage of Total Viewing Time That Peripheral Target is Perceived
Binocular visual confusion (unilateral opaque target)
73.56 Percentage of Time
Standard Deviation 17
Percentage of Total Viewing Time That Peripheral Target is Perceived
Unilateral monocular visual confusion (unilateral see-through target)
59.64 Percentage of Time
Standard Deviation 25.42
Percentage of Total Viewing Time That Peripheral Target is Perceived
Bilateral monocular visual confusion (bilateral see-through target)
87.81 Percentage of Time
Standard Deviation 13.85

Adverse Events

Visual Confusion

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Jaehyun Jung

Schepens Eye Research Institute of Massachusetts Eye and Ear

Phone: 6179122525

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place