Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA

NCT ID: NCT04955795

Last Updated: 2025-05-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

308 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-05-04

Study Completion Date

2027-09-30

Brief Summary

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This study is designed to examine the efficacy of a brief intervention plus a cognitive-behavioral intervention compared to brief intervention alone to address unhealthy alcohol use and comorbid mental health symptoms to improve HIV outcomes among people living with HIV in Alabama.

Detailed Description

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Participants will be randomly assigned to receive either Alcohol Brief Intervention (BI) or BI plus Common Elements Treatment Approach (T-CETA) via telephone. Participants will receive either 1 phone session of BI or 6 to 12 weekly phone sessions of BI + T-CETA. Follow ups will occur at 6 and 12 months with participants.

Participants will provide data on alcohol use, mental health comorbidities, HIV outcomes, medication adherence, and laboratory collections (CD4+ T cell count, viral load, and an alcohol biomarker: PEth) at the baseline assessment and again at the 6 and 12 month follow ups.

The study will also conduct mixed methods implementation measures with a subset of participants who are selected across various strata (i.e. gender, age, trial arm).

Conditions

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Hiv Alcohol Problem

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Alcohol Brief Intervention (BI)

At the time of trial enrollment, participants will receive a session of alcohol brief intervention (BI) via telephone.

Group Type ACTIVE_COMPARATOR

Alcohol Brief Intervention (BI)

Intervention Type BEHAVIORAL

The BI we will use was based on CETA's substance use module and was designed for one-on-one delivery. It is comprised of 6 elements (i.e. assessment, understanding impacts, exploring change, goal setting, identifying the reasons, and skill building) including a 2-week alcohol timeline follow back assessment, which is completed by the therapist. BI will be provided by a trained research assistant who has completed consent, enrollment, and randomized procedures with the client.

Common Elements Treatment Approach (CETA) via Telemedicine

Participants will be provided with 6 to 12 weekly CETA sessions via telephone.

Group Type EXPERIMENTAL

Alcohol Brief Intervention (BI)

Intervention Type BEHAVIORAL

The BI we will use was based on CETA's substance use module and was designed for one-on-one delivery. It is comprised of 6 elements (i.e. assessment, understanding impacts, exploring change, goal setting, identifying the reasons, and skill building) including a 2-week alcohol timeline follow back assessment, which is completed by the therapist. BI will be provided by a trained research assistant who has completed consent, enrollment, and randomized procedures with the client.

Common Elements Treatment Approach (CETA) via Telemedicine

Intervention Type BEHAVIORAL

CETA consists of nine key elements (i.e. engagement and education; safety assessment and planning; psychoeducation/introduction; substance use reduction; behavioral activation; cognitive coping/restructuring; relaxation; exposure; and problem solving) that address common mental health problems such as trauma, PTSD, depression, and anxiety. Participants randomized to CETA will be assigned to a CETA provider (clinical psychology or social work graduate student or master's degree substance abuse counselor). Enrolled participants will be discussed at weekly supervision meetings. An individualized treatment plan will be designed for each participant including type and order of CETA modules. The counselor will contact the participant by phone to schedule CETA sessions and follow up any missed appointments. Counselors, who will also be given a unique ID# for documentation and analysis, will carry 3-10 active CETA cases at a time depending on their experience level.

Interventions

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Alcohol Brief Intervention (BI)

The BI we will use was based on CETA's substance use module and was designed for one-on-one delivery. It is comprised of 6 elements (i.e. assessment, understanding impacts, exploring change, goal setting, identifying the reasons, and skill building) including a 2-week alcohol timeline follow back assessment, which is completed by the therapist. BI will be provided by a trained research assistant who has completed consent, enrollment, and randomized procedures with the client.

Intervention Type BEHAVIORAL

Common Elements Treatment Approach (CETA) via Telemedicine

CETA consists of nine key elements (i.e. engagement and education; safety assessment and planning; psychoeducation/introduction; substance use reduction; behavioral activation; cognitive coping/restructuring; relaxation; exposure; and problem solving) that address common mental health problems such as trauma, PTSD, depression, and anxiety. Participants randomized to CETA will be assigned to a CETA provider (clinical psychology or social work graduate student or master's degree substance abuse counselor). Enrolled participants will be discussed at weekly supervision meetings. An individualized treatment plan will be designed for each participant including type and order of CETA modules. The counselor will contact the participant by phone to schedule CETA sessions and follow up any missed appointments. Counselors, who will also be given a unique ID# for documentation and analysis, will carry 3-10 active CETA cases at a time depending on their experience level.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older
* Living with HIV infection
* Receiving HIV care at 1 of 4 participating AQMG sites (Alabama Quality Management Group sites - i.e. Ryan White HIV/AIDS Program-funded community clinics in Alabama)
* Unhealthy alcohol use documented on the AUDIT survey delivered via PRO (i.e. 4 or greater points for women and greater than 8 points for men).

Exclusion Criteria

* Inability to use a mobile phone due to cognitive or physical impairments
* Unable to speak sufficient English to provide informed consent and receive cognitive behavioral therapy
* Active suicidality or psychosis
* Risk for acute alcohol withdrawal or seizures
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

Sponsor Role collaborator

University of Alabama at Birmingham

OTHER

Sponsor Role lead

Responsible Party

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Karen Cropsey

Primary Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Karen Cropsey, Psy.D.

Role: PRINCIPAL_INVESTIGATOR

University of Alabama at Birmingham

Locations

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Health Service Center

Anniston, Alabama, United States

Site Status RECRUITING

UAB Family Clinic

Birmingham, Alabama, United States

Site Status RECRUITING

Thrive

Huntsville, Alabama, United States

Site Status RECRUITING

Five Horizons

Montgomery, Alabama, United States

Site Status RECRUITING

Unity Wellness

Opelika, Alabama, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Jahmil Harriette, Psy.D.

Role: CONTACT

205-975-4204

Facility Contacts

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Jahmil Harriette, Psy.D.

Role: primary

205-975-4204

Jahmil Harriette

Role: primary

Karen Cropsey

Role: backup

Jahmil Harriette, Psy.D.

Role: primary

205-975-4204

Jahmil Harriette

Role: primary

205-975-4204

Jahmil Harriette, Psy.D.

Role: primary

205-975-4204

Other Identifiers

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P01AA029540

Identifier Type: NIH

Identifier Source: secondary_id

View Link

IRB-300007410

Identifier Type: -

Identifier Source: org_study_id

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