Comparison of AOCT and AOPT for the Treatment of Medial Large Cystic OLT

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

46 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-03-01

Study Completion Date

2020-11-10

Brief Summary

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Autologous osteoperiosteal transplantation using tissue harvested from the iliac crest is used to treat large cystic osteochondral lesions of the talus. This study is to compare clinical and radiological outcomes between patients undergoing AOPT and those undergoing AOCT for large cystic OLTs.

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Detailed Description

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From March 2015 to March 2018, 23 patients who underwent AOPT and 23 patients who underwent AOCT to treat large cystic OLTs (\>10mm) were retrospectively evaluated. For comparability, the two groups were matched based on their demographics, including sex, age, body mass index, side of injury, follow-up period, and the preoperative cyst volume. Clinical outcomes were assessed using the visual analog scale (VAS), the American Orthopaedic Foot \& Ankle Society (AOFAS) score, and the Tegner score. Donor-site morbidity was recorded according to the symptoms, including pain, stiffness, swelling and discomfort. Radiological outcomes were evaluated using the Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) score, and the International Cartilage Repair Society (ICRS) score was obtained during second-look surgery.

Conditions

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Osteochondral Lesions of the Talus

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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AOPT

patients underwent AOPT to treat large cystic OLTs (\>10mm)

AOPT

Intervention Type PROCEDURE

The Osteochondral Autograft Transplant System (Arthrex) was used to create donor plugs. Osteoperiosteal grafts were harvested from the ipsilateral anterior superior iliac spine.

AOCT

patients underwent AOCT to treat large cystic OLTs (\>10mm)

AOCT

Intervention Type PROCEDURE

Osteochondral grafts were harvested from the non-weight-bearing zone of the ipsilateral anterolateral distal femur.

Interventions

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AOPT

The Osteochondral Autograft Transplant System (Arthrex) was used to create donor plugs. Osteoperiosteal grafts were harvested from the ipsilateral anterior superior iliac spine.

Intervention Type PROCEDURE

AOCT

Osteochondral grafts were harvested from the non-weight-bearing zone of the ipsilateral anterolateral distal femur.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* presence of medial large cystic OLTs (\>10 mm in diameter) confirmed by preoperative magnetic resonance imaging (MRI)
* patients who underwent either primary AOPT or AOCT

Exclusion Criteria

* small cystic OLTs
* ankle osteoarthritis
* ankle pigmented villonodular synovitis
* prior surgery on the ipsilateral ankle
* injuries or relevant trauma to the affected ankle after surgery

Eligible Sex

ALL

Accepts Healthy Volunteers

No