Low-Cost, Portable Flexible Nasopharyngoscope in Head & Neck Cancers in Low Resource Settings - Optimization Phase

NCT ID: NCT04905134

Last Updated: 2024-09-19

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

53 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-31

Study Completion Date

2023-09-22

Brief Summary

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This study aims to develop and evaluate a low-cost, portable, flexible nasopharyngeal scope (FNS) used to assess head and neck cancers (HNC) in low resource settings. The FNS will be compared to an endoscope that is used as standard of care (SOC) in terms of ease of use, image quality, and perceived pain. The ultimate goal is to compare the ease of use between the FNS to what is used in SOC.

Detailed Description

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Conditions

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Head and Neck Cancer Oral Cancer

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Patients evaluated using flexible nasopharyngoscope prototype device

Group Type ACTIVE_COMPARATOR

Nasopharyngoscope

Intervention Type DEVICE

Low-cost, flexible scope prototype will compared to standard of care scope used as standard of care.

Patients evaluated using standard of care nasopharyngoscope

Group Type NO_INTERVENTION

No interventions assigned to this group

Providers using flexible nasopharyngoscope prototype device

Group Type ACTIVE_COMPARATOR

Nasopharyngoscope

Intervention Type DEVICE

Low-cost, flexible scope prototype will compared to standard of care scope used as standard of care.

Interventions

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Nasopharyngoscope

Low-cost, flexible scope prototype will compared to standard of care scope used as standard of care.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Willing and able to provide signed and dated informed consent form
* Willing to comply with all study procedures and be available for the duration of the study
* Male or female, aged 18 or older
* Patients who clinical meet clinical criteria for SOC scope examination of the upper aerodigestive tract. This includes signs and symptoms such as dysphagia, nasal obstruction, neck mass, throat pain, and hoarseness.

Exclusion Criteria

* Withdrawal of consent during the study duration
* Subjects who have complications from the SOC exam
* Anyone unable to under the SOC exam
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Dental and Craniofacial Research (NIDCR)

NIH

Sponsor Role collaborator

Duke University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Walter Lee, MD

Role: PRINCIPAL_INVESTIGATOR

Duke Health

Locations

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Duke University Medical Center

Durham, North Carolina, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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1R01DE028555-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

Protocol Number: 22-136-E

Identifier Type: OTHER

Identifier Source: secondary_id

Pro00102912

Identifier Type: -

Identifier Source: org_study_id

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