Randomized Controlled Trial Assessing the Effect of Dexamethasone on Postoperative Function After Distal Radius Fixation
NCT ID: NCT04889547
Last Updated: 2023-10-23
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
EARLY_PHASE1
70 participants
INTERVENTIONAL
2021-07-10
2023-09-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
SINGLE_GROUP
TREATMENT
SINGLE
Study Groups
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Dexamethasone
Patient will receive intraoperative dexamethasone during distal radius open reduction and internal fixation
Dexamethasone
Intraoperative intravenous dexamethasone
No dexamethasone
Patient will not receive intraoperative dexamethasone during distal radius open reduction and internal fixation
No dexamethasone
No intraoperative intravenous dexamethasone
Interventions
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Dexamethasone
Intraoperative intravenous dexamethasone
No dexamethasone
No intraoperative intravenous dexamethasone
Eligibility Criteria
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Inclusion Criteria
* Willingness to comply with study procedures and
* Male or female greater than 18 years old
* American Society of Anesthesia class I/II/III
* Ability to take oral medicine in order to assess opioid regimen postop
* Distal radius open reduction and internal fixation surgery with single incision and volar plate
* Ability to consent for and receive a preoperative upper extremity nerve block by anesthesia
Exclusion Criteria
* Prescriptions for selective-serotonin reuptake inhibitors, gabapentin, duloxetine within 3 days of surgery
* History of diabetes and A1C \> 8
* Systemic glucocorticoids within 1 month of study enrollment
* Inability to take ibuprofen or acetaminophen due to allergy or condition
* History of hepatitis
* Pregnancy or lactation
* Allergic to opioids
* Known allergic reactions to components of IV dexamethasone
18 Years
ALL
Yes
Sponsors
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Northwell Health
OTHER
Responsible Party
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Locations
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North Shore University Hospital
Manhasset, New York, United States
Countries
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Other Identifiers
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21-0069
Identifier Type: -
Identifier Source: org_study_id
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