Clinical Value of Microvascular Ultrasonography in Real-time Differential Diagnosis of Thyrotoxic Patients
NCT ID: NCT04879173
Last Updated: 2021-05-10
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
50 participants
OBSERVATIONAL
2020-10-14
2022-10-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Precise discrimination between Graves' disease and painless thyroiditis/subacute thyroiditis is clinically very important in determining treatment methods, such as the prescription of antithyroid drugs. Primary endpoint was to verify the value of vascularity index, defined by Blood pixel in range of image / Total pixel in range of image .Seondary endpoint was to verify the superiority value of Microvascular flow imaging to discriminate thyrotoxicosis patients compared with Color doppler/ Power doppler ultrasound imaging and conventional ultrasound imaging.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Microvascular Profiling of Nodules in the Thyroid Gland
NCT07041307
Ultrasound Large-scale Model in Thyroid Field: A Multi-center Study on Medical-Engineering Integration
NCT07296575
HIFU Ablation vs Fixed-dose RAI-131 Therapy in Moderate-sized Non-toxic MNG
NCT04009863
Multiparameter Ultrasound Based-AI for the Diagnosis of Thyroid Nodules
NCT05816629
Artificial Intelligent Accelerates the Learning Curve for Mastering Contrast-enhanced Ultrasound of Thyroid Nodules
NCT05982821
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
The Microvascular flow imaging technology is expected to show higher sensitivity and accuracy than conventional color Doppler images in differentiating patients between Graves' disease and painless thyroiditis/subacute thyroiditis. We enrolled thyrotoxicosis patients in their initial presentation and used RS85 Ultrasound device manufactured by Samsung Medison to discriminate Graves' disease and painless thyroiditis/subacute thyroiditis. Power / Color doppler ultrasound imaging and conventional ultrasound imaging were used. Tranverse and longitudinal plane of the dominant lobe were selected for imaging. Doppler Adler's method was used to asscess vascularization. To assess the vascularity index, which is defined by Blood pixel in range of image / Total pixel in range of image, we selected the total tranverse plane of the thyroid as range of image.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_ONLY
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Hyperthyroidism caused by Graves' disease
RS85 Ultrasound device
RS85 Ultrasound device manufactured by Samsung Medison
Hyperthyroidism caused by painless/subacute thyroiditis
RS85 Ultrasound device
RS85 Ultrasound device manufactured by Samsung Medison
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
RS85 Ultrasound device
RS85 Ultrasound device manufactured by Samsung Medison
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
* Factitious thyrotoxicosis
* Unable for ultrasound
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Dong Jun Lim
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Dong Jun Lim
professor
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Dong Jun Lim, MD, PhD
Role: STUDY_DIRECTOR
the Catholic Univerisity of Korea
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Seoul St. Mary hospital
Seoul, , South Korea
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Dong Jun Lim, MD, PhD
Role: primary
References
Explore related publications, articles, or registry entries linked to this study.
Baek HS, Park JY, Jeong CH, Ha J, Kang MI, Lim DJ. Usefulness of Real-Time Quantitative Microvascular Ultrasonography for Differentiation of Graves' Disease from Destructive Thyroiditis in Thyrotoxic Patients. Endocrinol Metab (Seoul). 2022 Apr;37(2):323-332. doi: 10.3803/EnM.2022.1413. Epub 2022 Apr 13.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
Project name 2
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.