The Relationship Between Zonulin and Interleukin-8 Levels and Postoperative Delirium Development
NCT ID: NCT04875182
Last Updated: 2025-09-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
73 participants
OBSERVATIONAL
2021-05-01
2021-09-02
Brief Summary
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Detailed Description
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Postoperative pain scores of the patients will recorded by using a numerical rating scale (NRS).
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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group delirium
Patients who are over 65 years of age and scheduled for femur fixation surgery will be included in the study. Blood samples for zonulin and interleukin-8 levels will be taken at the day prior to the surgery. All patients will be evaluated by Delirium Rating Scale for delirium development at the postoperative 1., 2. and 3. days. Patients with a Delirium Rating Scale-Revised-98 score of 11 points or higher will be included in the Group Delirium. And second blood samples for zonulin and interleukin-8 levels will be taken at the time of diagnosis.
Postoperative pain scores of the patients will recorded by using a numerical rating scale.
Evaluation of Delirium development
Postoperative pain scores of the patients will recorded by using a numerical rating scale.
group control
Patients who are over 65 years of age and scheduled for femur fixation surgery will be included in the study. Blood samples for zonulin and interleukin-8 levels will be taken at the day prior to the surgery. All patients will be evaluated by Delirium Rating Scale for delirium development at the postoperative 1., 2. and 3. days. Patients with a Delirium Rating Scale-Revised-98 score under 11 points for postoperative 72 hours will be included in the Group Control. And second blood samples for zonulin and interleukin-8 levels will be taken at the postoperative 72. hour.
Postoperative pain scores of the patients will recorded by using a numerical rating scale.
Evaluation of Delirium development
Postoperative pain scores of the patients will recorded by using a numerical rating scale.
Interventions
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Evaluation of Delirium development
Postoperative pain scores of the patients will recorded by using a numerical rating scale.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
65 Years
ALL
No
Sponsors
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Dr. Gokhan Vural
OTHER
Responsible Party
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Dr. Gokhan Vural
Anesthesiologist Dr. Gokhan
Principal Investigators
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Gökhan vural
Role: PRINCIPAL_INVESTIGATOR
Muğla Sıtkı Koçman University
Locations
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Muğla Sıtkı Koçman University
Muğla, Menteşe, Turkey (Türkiye)
Countries
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Other Identifiers
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26.02.2020- 04/VI
Identifier Type: -
Identifier Source: org_study_id
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