Role of Gray Scale and Color Doppler Ultrasound in Diagnosis of Pediatric Neck Masses

NCT ID: NCT04856020

Last Updated: 2021-04-22

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 96 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-04-30
• Study Completion Date: 2023-05-31

Brief Summary

Our aim is to assess the role of the gray scale and color Doppler ultrasound in diagnosis of the different pediatric neck masses .

Detailed Description

Neck masses are a common occurrence in the pediatric population and often represent a diagnostic challenge for the clinician involved . fortunately , the vast majority of these lesions are ultimately proven to be benign in nature (1).

Even though clinical examination and patient's history are the first and indispensable steps in the initial diagnosis, the role of imaging is crucial, not only to determine whether a mass represents a true tumour or not , but also to achieve a more correct diagnosis and determine the extension of the lesion and its relation with the nearby anatomic structures (2).

Ultrasound (US) should serve as the primary initial imaging modality in children for palpable masses and assessment of superficial glandular structures. Because of the smaller neck size and less subcutaneous fat, sonographic penetration and resolution is generally improved as compared with adults (3 ).

Doppler imaging can also elucidate how flow is distributed within a mass may have diagnostic significance and help us in determining the nature of the lesion as well as it is of great importance in assessment of vascular lesions (4)

Though ultrasound is most common method used for evaluation of pediatric neck masses , and CT as well as MRI are used as an additional tool when necessary ( 3 ) , few studies have looked at the sensitivity and specificity of the different imaging modalities of the pediatric neck masses and most studies have investigated the epidemiology of the pediatric neck masses (5) which make histopathological diagnosis still the gold standard in distinguishing the etiology of pediatric neck masses and ruling out malignant disease (6)

Conditions

Pediatric Tumor

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Clinical cases who are suspected for and provisionally diagnosed for "neck swelling" in children (below age of 18 years).

Exclusion Criteria

1. Patients with conditions that may hinder ultrasound examination like subcutaneous emphysema and thick skin scarring.

2. Patients who are unwilling/uncooperative or have not given consent for participation.

• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Monica Sobhy Khalaf Boles

Principal investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Samy AbdElAziz, PhD

Role: STUDY_CHAIR

Assiut University

Hazem Abo Zeid, PhD

Role: STUDY_DIRECTOR

Assiut University

Central Contacts

Monica Sobhy

Role: CONTACT

monica.sobhy94@gmail.com

+2001278489110

References

Riva G, Sensini M, Peradotto F, Scolfaro C, Di Rosa G, Tavormina P. Pediatric neck masses: how clinical and radiological features can drive diagnosis. Eur J Pediatr. 2019 Apr;178(4):463-471. doi: 10.1007/s00431-018-3305-9. Epub 2019 Jan 14.

Reference Type: BACKGROUND

PMID: 30643937 (View on PubMed)

Toma P, Esposito F, Granata C, Paolantonio G, Terranova MC, Lo Re G, Ferrara D, Rollo M, Zeccolini M, Salerno S. Up-to-date imaging review of paediatric soft tissue vascular masses, focusing on sonography. Radiol Med. 2019 Oct;124(10):935-945. doi: 10.1007/s11547-019-01050-8. Epub 2019 Jun 11.

Reference Type: BACKGROUND

PMID: 31187354 (View on PubMed)

Friedman ER, John SD. Imaging of pediatric neck masses. Radiol Clin North Am. 2011 Jul;49(4):617-32, v. doi: 10.1016/j.rcl.2011.05.005.

Reference Type: BACKGROUND

PMID: 21807165 (View on PubMed)

Stern JS, Ginat DT, Nicholas JL, Ryan ME. Imaging of pediatric head and neck masses. Otolaryngol Clin North Am. 2015 Feb;48(1):225-46. doi: 10.1016/j.otc.2014.09.015.

Reference Type: BACKGROUND

PMID: 25439556 (View on PubMed)

Other Identifiers

Us in pediatric neck masses

Identifier Type: -

Identifier Source: org_study_id