The Guidance of Thin Cross- Section of CT in Anatomic Segmentectomy

NCT ID: NCT04842578

Last Updated: 2021-04-13

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 200 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2019-09-01
• Study Completion Date: 2021-03-30

Brief Summary

Three-dimensional (3D) simulation of pulmonary vessels and the space between the lesion and adjacent tissues is regarded improving the safety and accuracy of video-assisted thoracoscopic surgery (VATS) for segmentectomy for ground glass opacity (GGO) in lung. However, not every thoracic surgeon can handle the technique, in addition, the 3D reconstruction originate from the thin CT scan. Actually, the investigators found that, the reading and comprehension of the thin cross- section of CT can guide the accurate anatomic segmentectomy in most situations. The investigators designed a retrospective study to compare the reading of thin cross- section of CT with 3D reconstruction or without 3D reconstruction during the guidance of anatomic segmentectomy.

Conditions

Segmentectomy; Video- Assisted Thoracoscopic Surgery; Three-dimensional-computed Tomography (3D-CT); Thin Cross- Section of CT

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: DOUBLE

Study Groups

group of thin cross- section of CT

Anatomic Segmentectomy with the Guidance of Thin Cross- Section of CT

Group Type: EXPERIMENTAL

Cross- Section of CT Guided Anatomic Segmentectomy

Intervention Type: OTHER

The anatomic segmentectomy is base on the reading and comprehension of Cross- Section of CT.

group of thin 3D simulation

Anatomic Segmentectomy with the Guidance of 3D simulation

Group Type: ACTIVE_COMPARATOR

3D simulation Guided Anatomic Segmentectomy

Intervention Type: OTHER

The anatomic segmentectomy is base on the overview of 3D simulation of pulmonary structure.

Interventions

Cross- Section of CT Guided Anatomic Segmentectomy

The anatomic segmentectomy is base on the reading and comprehension of Cross- Section of CT.

Intervention Type: OTHER

3D simulation Guided Anatomic Segmentectomy

The anatomic segmentectomy is base on the overview of 3D simulation of pulmonary structure.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

Selection criteria for VATS segmentectomy in the present study were as follows:

(I) patients with single peripheral GGO lesion considered suspicious for malignancy;

(II) the lesion <2 cm in diameter and with at least one of the followings:

(i) pure adenocarcinoma in situ (AIS) histology;

(ii) nodule has ≥50% ground-glass appearance on high resolution CT;

(iii) radiologic surveillance conforms a long doubling time (≥400 days).

Exclusion Criteria

(I) patients with insufficient cardiopulmonary function;

(II) other contraindication for segmentectomy.

• Minimum Eligible Age: 25 Years
• Maximum Eligible Age: 85 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

The Second Hospital of Shandong University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Xiaogang Zhao

Role: STUDY_DIRECTOR

The Second Hospital of Shandong University

Locations

The Second Hospital of Shandong University

Jinan, Shandong, China

Countries

China

Other Identifiers

thin cross- section of CT ZYP

Identifier Type: -

Identifier Source: org_study_id