Measuring Beliefs and Norms About Persons With Alcohol Use Disorder

NCT ID: NCT04832321

Last Updated: 2023-10-19

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 1363 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-02-19
• Study Completion Date: 2022-08-15

Brief Summary

Survey experiment to estimate drivers of stigma toward people with alcohol use disorder

Detailed Description

Despite significant advances in scientific understanding of substance use disorders accompanied by significant advances in treatment and improvements in prognosis, substance use disorder remains highly stigmatized throughout the world. Previous studies suggest that portraying alcohol use disorder as treatable can reduce negative attitudes toward persons with alcohol use disorder. This randomized controlled trial compares the effects of exposing study participants to vignettes portraying persons with untreated and symptomatic alcohol use disorder vs. treated alcohol use disorder with complete response vs. treated alcohol use disorder with relapse, with and without adverse economic impacts. It is hypothesized, based on prior work, that study participants exposed to vignettes depicting treated alcohol use disorder with completed response would have the greatest effect on reducing negative attitudes toward persons with alcohol use disorder, followed by treated alcohol use disorder with relapse and untreated and symptomatic alcohol use disorder, and that adverse economic impacts will exacerbate negative attitudes toward persons with alcohol use disorder.

Conditions

Alcohol Use Disorder (AUD)

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: DOUBLE

Study Groups

No intervention: V1: Control

This version of the survey questionnaire depicts a young man with no symptoms of alcohol use disorder

Group Type: NO_INTERVENTION

No interventions assigned to this group

Experimental: V2: Alcohol Use Disorder

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder.

Group Type: EXPERIMENTAL

Survey questionnaire

Intervention Type: OTHER

Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Experimental: V3: Alcohol Use Disorder + Treatment with Response

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder who is successfully treated with complete response.

Group Type: EXPERIMENTAL

Survey questionnaire

Intervention Type: OTHER

Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Experimental: V4: Alcohol Use Disorder + Treatment with Relapse

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder who is successfully treated with partial relapse.

Group Type: EXPERIMENTAL

Survey questionnaire

Intervention Type: OTHER

Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Experimental: V5: Alcohol Use Disorder + Economic Impact

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder whose untreated alcohol use disorder negatively affects his family's finances.

Group Type: EXPERIMENTAL

Survey questionnaire

Intervention Type: OTHER

Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Experimental: V6: Alcohol Use Disorder + Economic Impact + Treatment with Response

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder whose untreated alcohol use disorder negatively affects his family's finances, who is then successfully treated with complete response.

Group Type: EXPERIMENTAL

Survey questionnaire

Intervention Type: OTHER

Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Experimental: V7: Alcohol Use Disorder + Economic Impact + Treatment with Relapse

As this is a survey experiment, the "intervention" involves random assignment to a survey questionnaire with specific wording. This version of the survey questionnaire depicts a young man with symptomatic, untreated alcohol use disorder whose untreated alcohol use disorder negatively affects his family's finances, who is then successfully treated with partial relapse and continued negative economic impact.

Group Type: EXPERIMENTAL

Survey questionnaire

Intervention Type: OTHER

Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Interventions

Survey questionnaire

Each version of the questionnaire portrays a young Ugandan man with different profiles of illness severity, treatment, and treatment response.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• All adults who consider Nyakabare their primary place of residence and who are capable of providing consent

Exclusion Criteria

• Minors younger than 18 years of age, with the exception of emancipated minors
• Persons who do not consider Nyakabare Parish their primary place of residence, e.g., persons who happen to be visiting Nyakabare at the time of the survey or who own a home in Nyakabare but spend most of their time outside the parish
• Persons with psychosis, neurological damage, acute intoxication, or other cognitive impairment (all of which are determined informally in the field by non-clinical research staff in consultation with a supervisor)

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Mbarara University of Science and Technology

OTHER

Sponsor Role: collaborator

Massachusetts General Hospital

OTHER

Sponsor Role: lead

Responsible Party

Alexander Tsai

Associate Professor of Psychiatry

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Alexander C Tsai, MD

Role: PRINCIPAL_INVESTIGATOR

Massachusetts General Hospital

Locations

Mbarara University of Science and Technology

Mbarara, , Uganda

Countries

Uganda

Other Identifiers

2013P000395_1

Identifier Type: -

Identifier Source: org_study_id