Motivational Interviewing to Reduce Substance Use Among Depression Patients
NCT ID: NCT02420561
Last Updated: 2015-06-10
Study Results
Results pending
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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Recruitment Status
COMPLETED
Clinical Phase
NA
Total Enrollment
307 participants
Study Classification
INTERVENTIONAL
Study Start Date
2010-10-31
Study Completion Date
2014-08-31
Brief Summary
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The study aims to evaluate the effectiveness of an intervention to reduce alcohol and drug use and depression symptoms, improve functional status and promote appropriate health services utilization, in a sample of 300 adults seeking treatment for depression who also report hazardous drinking or drug use with depression.
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Detailed Description
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This study addresses important questions regarding how to identify and treat patients in Psychiatry who present for services with alcohol or drug use that may exacerbate depression. The investigators propose a study of Brief Motivational Intervention (BMI) to reduce drug and alcohol use among patients with depression, and to enhance engagement with a Kaiser Chemical Dependency Recovery Program (CDRP) as needed. Patients with depression who use drugs or alcohol even at sub-diagnostic levels are at high risk for escalation of substance problems. BMI is an innovative, evidence-based approach that could decrease drug and alcohol use and improve outcomes. But it has not been tested among depression patients. This study sample will include 300 outpatients in treatment for depression in Kaiser Permanente Northern California Hayward/Fremont Psychiatry. Inclusion criteria are based on drug use (any illicit drug use and non-prescribed use of prescription drugs) and hazardous drinking (i.e., ≥ 3 drinks in a day for women and ≥ 4 drinks in a day for men), and moderate to severe depression symptoms at intake. Three hundred patients will be randomized to receive one in-person BMI session and two telephone BMI sessions within 6 weeks of intake (intervention) or a brochure on risks of drug and alcohol use (control). The investigators anticipate that the intervention will be effective in reducing frequency of drug use and hazardous drinking at 3-, 6-, and 12-month telephone follow-up interviews; improving mood and functional outcomes; increasing depression treatment retention (number of psychiatry visits, based on Healthcare Effectiveness Data and Information Set (HEDIS) standards); and facilitating patient initiation of chemical dependency program treatment if needed, and will be cost effective. For the improvement of patient care, it will also yield important information on integrating alcohol and drug intervention in Psychiatry and how best to help patients access specialty CDRP services when needed.
Conditions
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Depression
Substance-Related Disorders
Study Design
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Allocation Method
RANDOMIZED
Intervention Model
PARALLEL
Primary Study Purpose
HEALTH_SERVICES_RESEARCH
Blinding Strategy
NONE
Study Groups
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Motivational Interviewing
The motivational interviewing (MI) intervention consisted of one 45-minute in-person MI session followed by two 15-minute telephone "booster" sessions
Group Type
EXPERIMENTAL
Motivational Interviewing
Intervention Type
BEHAVIORAL
* One in-person motivational interviewing session intervention that lasts for 45-minutes
* Additional two 15-minute telephone "booster" sessions post in-person 45 minute sessions
Control
Participants received a brochure on alcohol and drug use risks.
Group Type
ACTIVE_COMPARATOR
Control (brochure)
Intervention Type
BEHAVIORAL
Participants received a brochure on alcohol and drug use risks.
Interventions
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Motivational Interviewing
* One in-person motivational interviewing session intervention that lasts for 45-minutes
* Additional two 15-minute telephone "booster" sessions post in-person 45 minute sessions
Intervention Type
BEHAVIORAL
Control (brochure)
Participants received a brochure on alcohol and drug use risks.
Intervention Type
BEHAVIORAL
Eligibility Criteria
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Inclusion Criteria
* Hazardous drinking (i.e., ≥ 3 drinks in a day for women and ≥ 4 drinks in a day for men)
* Drug use (including any illicit drug use and non-prescribed use of prescription drugs in the prior 30 days)
* Moderate or greater symptoms of depression based on a score of ≥ 5 on the Patient Health Questionnaire (PHQ-9)
* Drug use (including any illicit drug use and non-prescribed use of prescription drugs in the prior 30 days)
* Moderate or greater symptoms of depression based on a score of ≥ 5 on the Patient Health Questionnaire (PHQ-9)
Exclusion Criteria
* Current mania or psychosis
Minimum Eligible Age
18 Years
Eligible Sex
ALL
Accepts Healthy Volunteers
No
Sponsors
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Kaiser Foundation Research Institute
OTHER
Sponsor Role
collaborator
University of California, San Francisco
OTHER
Sponsor Role
lead
Responsible Party
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Responsibility Role
SPONSOR
Principal Investigators
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Derek D Satre, PhD
Role: PRINCIPAL_INVESTIGATOR
University of California, San Francisco
Locations
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Kaiser Permanente Medical Center Southern Alameda County
Union City, California, United States
Site Status
Countries
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United States
References
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Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
10-03323
Identifier Type: -
Identifier Source: org_study_id
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