Drug Allergy Labels After Drug Allergy Investigation

NCT ID: NCT04827602

Last Updated: 2022-05-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

849 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-04-15

Study Completion Date

2021-07-15

Brief Summary

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The aim of this study is to investigate the degree of match between the drug allergy label in the hospital's electronic health record and primary care's electronic health record among patients who previously have been drug allergy tested.

Detailed Description

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Patients who previously have been penicillin allergy tested in 2017 to 2019 at the Allergy Clinic at Gentofte Hospital is included in the study. Patients are identified through a drug allergy database at the department.

A letter describing the study and the data collection process will be sent to the patients' General Practice offices (GP).

Data collection: The patients GP's are contacted by telephone where the information about the drug allergy labels in their electronical medical charts are shared. On the same day as the phone contact to the GP's office, the patient's electronical health record in the hospital system is accessed in order to gain information about the current drug allergy registrations.

Predictors for the explanatory analysis is collected partly through the phone call to the GP (such as numbers of patients and physicians at each GP and the electronic health system used), from the hospital electronic health record (such as number of hospital admissions since drug allergy testing) and from the drug allergy database.

Conditions

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Drug Hypersensitivity

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Allergy tested group

Patients who have completed penicillin allergy testing

Drug allergy label status in electronic health records

Intervention Type OTHER

Registered drug allergy labels in primary care and hospital electronic medical charts

Interventions

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Drug allergy label status in electronic health records

Registered drug allergy labels in primary care and hospital electronic medical charts

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Penicillin allergy tested at the Allergy Clinic, Copenhagen University Hospital - Herlev and Gentofte, Copenhagen, Denmark in 2017-2019

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Research Unit Of General Practice, Copenhagen

OTHER

Sponsor Role collaborator

University Hospital, Gentofte, Copenhagen

OTHER

Sponsor Role lead

Responsible Party

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Sara Fransson

Ph.D student

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lene H. Garvey

Role: PRINCIPAL_INVESTIGATOR

Allergy Clinic, Copenhagen University Hospital, Copenhagen

Locations

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Allergy Clinic, Department of Dermato-Allergology, Copenhagen University Hospital

Copenhagen, , Denmark

Site Status

Countries

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Denmark

References

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Lachover-Roth I, Sharon S, Rosman Y, Meir-Shafrir K, Confino-Cohen R. Long-Term Follow-Up After Penicillin Allergy Delabeling in Ambulatory Patients. J Allergy Clin Immunol Pract. 2019 Jan;7(1):231-235.e1. doi: 10.1016/j.jaip.2018.04.042. Epub 2018 May 22.

Reference Type RESULT
PMID: 29800754 (View on PubMed)

Vyles D, Chiu A, Routes J, Castells M, Phillips EJ, Kibicho J, Brousseau DC. Antibiotic Use After Removal of Penicillin Allergy Label. Pediatrics. 2018 May;141(5):e20173466. doi: 10.1542/peds.2017-3466.

Reference Type RESULT
PMID: 29678929 (View on PubMed)

Sacco KA, Bates A, Brigham TJ, Imam JS, Burton MC. Clinical outcomes following inpatient penicillin allergy testing: A systematic review and meta-analysis. Allergy. 2017 Sep;72(9):1288-1296. doi: 10.1111/all.13168. Epub 2017 Apr 26.

Reference Type RESULT
PMID: 28370003 (View on PubMed)

Other Identifiers

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GEH-R-20068776

Identifier Type: -

Identifier Source: org_study_id

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