Study of the Role of Hemostasis in Perioperative Anaphylaxis

NCT ID: NCT04825158

Last Updated: 2021-04-01

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 30 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-04-01
• Study Completion Date: 2024-02-09

Brief Summary

Anaphylaxis is a severe and life-threatening complication during the perioperative period. Perioperative anaphylaxis is still associated with a significant mortality despite quick and efficient management using epinephrine, the mainstay of acute treatment. Experimental data and few case reports are suggesting that hemostasis, and more precisely platelets, could play a role in anaphylaxis. Our main hypothesis is that activation of the hemostatic system contributes to the severity of the reaction

Conditions

Hemoptysis; Perioperative Complication; Anaphylaxis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Patient, male or female, adult
• In the perioperative period
• In whom the diagnosis of anaphylactic shock is suggested
• Patient is giving his consent to participate in the study

Exclusion Criteria

• Subject under legal protection
• Subject under guardianship or guardianship
• Anemia less than 7 g /dl at the time of inclusion

• Minimum Eligible Age: 2 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University Hospital, Strasbourg, France

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Central Contacts

Charles-Ambroise TACQUARD, PHD

Role: CONTACT

charlesambroise.tacquard@chru-strasbourg.fr

+333 69 55 16 08

Xavier DELABRANCHE, PHD

Role: CONTACT

Xavier.delabranche@chru-strasbourg.fr

03.69.55.09.36

Other Identifiers

8030

Identifier Type: -

Identifier Source: org_study_id