Effects of Home-based Exercise in Parkinson's Disease

NCT ID: NCT04810897

Last Updated: 2021-03-23

Basic Information

• Recruitment Status: UNKNOWN
• Total Enrollment: 20 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-07-01
• Study Completion Date: 2021-11-30

Brief Summary

Home-based exercise program focusing on axial rigidity could be used as an adjunct rehabilitation program to improve rotational movement, gait and functional movement associated with axial rigidity in individuals with PD.

Detailed Description

Typically, individuals with PD revert to more primitive movement patterns, which lack many of the automatic postural adjustments and axial movements that accompany simple activities, such as supine to standing, getting up from sitting or turning over in bed. The present study is designed to allow patients and their relatives to perform exercises by themselves conveniently at home. The results were considered a vital component of a complex intervention and were played an integral part in the implementation process of exercises in functional performance. Furthermore, this study will prove sufficient high-quality evidence to investigate whether improvements in function due to exercise-based rehabilitation are associated with reducing axial rigidity in individuals with PD.

Currently, there is a lack of evidence for the effectiveness of home-based exercise programs in PD patients in Thailand. For the present study, we devised a home-based 10-week exercise program focusing on segmental rotation and task-specific movements for turning practice to determine effects on axial mobility and turning. The aimed of this study to examine the effects of a 10-week task specific home-based exercise program on turning kinematics, gait and stepping characteristics, the Functional Reach test (FRT), the Unified Parkinson's Disease Rating Scale (UPDRS), the Freezing of Gait questionnaire (FOG) and the Fall Efficacy Scale International (FES-I) in individuals with PD.

Conditions

Parkinson Disease

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Parkinson's disease

The neurologists will inform the individuals with PD that we are doing this research and we will attach the research advertisement at Movement Disorder Clinic, Division of Neurology, Faculty of Medicine Siriraj Hospital, Mahidol University, Thailand. Only individuals with PD who meet the inclusion and exclusion criteria will be invited to participate in the study. The researcher will inform participants about the purpose, procedure, and advantage of the study prior to participation in the study. Individuals with PD will be asked to sign an informed consent if they agree to participate in the study.

Exercise

Intervention Type: OTHER

Exercise programme is reported in the clinical trial registration number is NCT03473834.

Interventions

Exercise

Exercise programme is reported in the clinical trial registration number is NCT03473834.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Clinically diagnosed with PD stages 1.5 to 3 as assessed by the modified Hoehn and Yahr scale
• The age groups between 50 and 75 years
• Taking PD medication regularly for at least a month
• No signs of wearing-off phenomenon
• Able to walk independently without any assistive device and 6) able to follow commands and instructions

Exclusion Criteria

• Clinically diagnosed with dementia or other neurological or cardiopulmonary diseases
• Musculoskeletal problems that could influence the test performance such as arthritis or severe leg pain
• High blood pressure (more than 140/90 mmHg)
• Haemodialysis
• Visual problems that could not be adjusted with lenses or glasses
• Taking medicine which affected to functional movement.

• Minimum Eligible Age: 60 Years
• Maximum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Mahidol University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Fuengfa Khobkhun

Role: PRINCIPAL_INVESTIGATOR

Physical Therapy

Locations

Fuengfa Khobkhun

Nakhon Pathom, , Thailand

Site Status: RECRUITING

Countries

Thailand

Central Contacts

Fuengfa Khobkhun, PhD

Role: CONTACT

fuengfa.kho@mahidol.edu

+66953539196

Facility Contacts

Fuengfa Khobkhun, PhD

Role: primary

fuengfa.kho@mahidol.edu

+66953539196

Other Identifiers

MU-CIRB 2020/048.1902

Identifier Type: -

Identifier Source: org_study_id