The Effectiveness of Peripheral Magnetic Stimulation in Men With Lower Urinary Tract Symptoms

NCT ID: NCT04807569

Last Updated: 2021-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-04-01

Study Completion Date

2022-04-01

Brief Summary

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The main hypothesis of this study is that peripheral magnetic neuromodulation can correct the symptoms of lower urinary tract in men. We assume that under the influence of t peripheral magnetic stimulation, both the subjective state of patients assessed by standardized questionnaires and a urination diary, as well as the objective parameters, assessed by non-invasive urodynamic studies, will be improved. This study will use standard protocols built into the BTL Emsella magnetic stimulator.

Detailed Description

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The aim of the study is to test the hypothesis that the use of the peripheral magnetic stimulation in men with lower urinary tract symptoms will help to reduce subjective and objective clinical symptoms and improve the quality of life of patients.

Conditions

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Bladder Hypersensitivity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Experimental group

10 sessions of non-invasive peripheral magnetic neuromodulation using the BTL Emsella magnetic stimulator according to the manufacturer's standard protocol: "pelvic floor rehabilitation".

Group Type EXPERIMENTAL

Peripheral magnetic neuromodulation

Intervention Type OTHER

Non-invasive peripheral magnetic neuromodulation using the BTL Emsella magnetic stimulator according to the manufacturer's standard protocol: "pelvic floor rehabilitation

Control group

one-month course of drug therapy with alpha-1-adrenoblocker according to the standard scheme

Group Type EXPERIMENTAL

Taking drug Tamsulosin

Intervention Type DRUG

Tamsulosin at a dose of 0.4 mg x 1 time per day orally for 1 month.

Interventions

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Peripheral magnetic neuromodulation

Non-invasive peripheral magnetic neuromodulation using the BTL Emsella magnetic stimulator according to the manufacturer's standard protocol: "pelvic floor rehabilitation

Intervention Type OTHER

Taking drug Tamsulosin

Tamsulosin at a dose of 0.4 mg x 1 time per day orally for 1 month.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Age \> 18 years;
2. Signed informed consent;
3. The presence of lower urinary tract symptoms: urinary frequency, nocturia, urgency; feeling of incomplete bladder, weak urine stream.

Exclusion Criteria

1. The patient, who have been implanted devices that control physiological functions (a pacemaker, a device for deep brain stimulation and chronic epidural brain stimulation, a cochlear implant).
2. Convulsive attacks in the anamnesis;
3. Taking medications that may trigger the risk of seizures;
4. The presence in the patient's body of metal elements or objects made with the use of ferromagnets (joint prostheses, eye prostheses, tattoos made using metal ink, surgical clips, staples and other metal suture materials, etc.)
5. Chronic cardiovascular and cerebrovascular diseases in the stage of decompensation or recent acute conditions (myocardial infarction, brain stroke, etc.)
6. The presence of infravesical obstruction in men, determined by uroflowmetry (obstructive urination curve according to the Liverpool nomogram);
7. The postvoid residual volume (more than 50 ml);
8. The concentration of prostate specific antigen (PSA) in the blood is more than 4.0 ng / ml;
9. The presence of urinary tract infection;
10. A history of cancer of the pelvic floor organs;
Minimum Eligible Age

25 Years

Maximum Eligible Age

75 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Joint-Stock Company North-West Center for Evidence-Based Medicine, Russian Federation

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Joint-Stock Company "North-Western Centre of Evidence-Based Medicine"

Saint Petersburg, , Russia

Site Status

Countries

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Russia

Central Contacts

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Gleb Kovalev, MD

Role: CONTACT

+78126004712

Dmitriy Shkarupa, Phd

Role: CONTACT

+78126004712

Other Identifiers

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2/2021

Identifier Type: -

Identifier Source: org_study_id

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