Free Middle Turbinate Flap for Repair of Low Flow Cerebrospinal Fluid Leak
NCT ID: NCT04784169
Last Updated: 2021-03-05
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
100 participants
INTERVENTIONAL
2021-04-30
2023-01-31
Brief Summary
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Detailed Description
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Multiple graft materials have been employed in the approach, including temporalis fascia, middle turbinate flap, fascia lata, fat, free cartilage or bone, vascularized nasoseptal flap and acellular skin grafts. Among these options, vascular nasoseptal flaps are the most popular materials at present. Limited literature has been reported the use of free middle turbinate flap during an endoscopic approach to treat CSF rhinorrhea, and the results were inconclusive. There were a large number of cases using free middle turbinate flap for CSF rhinorrhea repair in our institution. The purpose of this study was to determine the efficacy and safety of the free middle turbinate flap for repair of CSF rhinorrhea.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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free middle turbinate flap group
A free middle turbinate flap is used to repair the leakage
free middle turbinate flap
Repairing low flow leak using free middle turbinate flap
vascularized nasoseptal flap
A vascularized nasoseptal flap is used to repair the leakage
vascularized nasoseptal flap
Repairing low flow leak using fascia lata
Interventions
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free middle turbinate flap
Repairing low flow leak using free middle turbinate flap
vascularized nasoseptal flap
Repairing low flow leak using fascia lata
Eligibility Criteria
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Inclusion Criteria
* Dural defect smaller than 1cm
* No extensive arachnoid dissection
* No dissection into a ventricle or cistern
Exclusion Criteria
ALL
No
Sponsors
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
OTHER
Responsible Party
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Qiangping Wang
MD
Principal Investigators
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GAO HUI
Role: STUDY_CHAIR
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Locations
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GAO HUI
Wuhan, Hubei, China
Countries
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Central Contacts
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Facility Contacts
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GAO HUI
Role: primary
Other Identifiers
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20210086
Identifier Type: -
Identifier Source: org_study_id
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