FDFG Versus SMAS Flap After Superficial Parotidectomy; Evaluation of Functional and Esthetic Outcome

NCT ID: NCT05452837

Last Updated: 2022-07-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

78 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-02-01

Study Completion Date

2021-10-31

Brief Summary

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After parotidectomy, Frey's syndrome and facial disfigurement are the most common encountered complications. Free dermal fat graft (FDFG) and the superficial musculoaponeurotic system (SMAS) flap, have very promising results. In this study, the functional and esthetic outcome from their usage were compared.

Detailed Description

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Parotidectomy is the standard procedure for treatment of many parotid lesions, however it carries a lot of drawbacks. Facial asymmetry and Frey's syndrome are the most annoying complications to the patients. Insertion of inter-positioning grafts at parotidectomy bed can decrease these complications significantly. Free dermal fat graft (FDFG) and the superficial musculoaponeurotic system (SMAS) flap, have very promising results. In this study the investigators have compared the functional and esthetic outcome from their usage.

Seventy-eight patient underwent parotidectomy for various causes. The patients were divided randomly in 2 groups each group 39 patients. In one group FDFG was inserted at the parotidectomy bed, while in the other group SMAS flap was performed. Preoperative, operative, and postoperative data were recorded and analyzed.

The normality of distribution of variables was verified by Wilks -Shapiro test. The data were expressed as Number (No), percentage (%) mean (x̅) and standard deviation (SD). Chi-square test (χ2) was used to study association between qualitative variables. Whenever any of the expected cells were less than five, Fischer's Exact test was used. Student's t-test is a test of significance used for comparison of quantitative variables between two groups of normally distributed data, while Mann Whitney's test was used for comparison of quantitative variables between two groups of not normally distributed data. Two-sided P value was set to be significant if \< 0.05.

Conditions

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Frey Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Free Dermal Fat Graft

Free Dermal Fat Graft (FDFG) is applied to the superficial parotidectomy defect site

Group Type ACTIVE_COMPARATOR

FDFG

Intervention Type PROCEDURE

FDFG is applied to the parotidectomy bed after superficial parotidectomy

Superficial musculoaponeurotic system flap

Superficial musculoaponeurotic system (SMAS) Flap is dissected and tailored to fill the defect after superficial parotidectomy

Group Type ACTIVE_COMPARATOR

SMAS

Intervention Type PROCEDURE

SMAS flap is applied to the parotidectomy bed after superficial parotidectomy

Interventions

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FDFG

FDFG is applied to the parotidectomy bed after superficial parotidectomy

Intervention Type PROCEDURE

SMAS

SMAS flap is applied to the parotidectomy bed after superficial parotidectomy

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients indicated for superficial parotidectomy

Exclusion Criteria

* Less than 18 years of age
* Proved malignant parotid tumor
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Menoufia University

OTHER

Sponsor Role lead

Responsible Party

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M. Ashraf Balbaa

Professor of Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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M. Ashraf Balbaa, M.D.

Role: PRINCIPAL_INVESTIGATOR

Faculty of Medicine, Menoufia University

Locations

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Faculty of Medicine, Menoufia University

Shibīn al Kawm, , Egypt

Site Status

Countries

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Egypt

References

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Curry JM, King N, Reiter D, Fisher K, Heffelfinger RN, Pribitkin EA. Meta-analysis of surgical techniques for preventing parotidectomy sequelae. Arch Facial Plast Surg. 2009 Sep-Oct;11(5):327-31. doi: 10.1001/archfacial.2009.62.

Reference Type RESULT
PMID: 19797095 (View on PubMed)

Fawzy A, Balbaa MA, Hagag M. Evaluation of functional and aesthetic outcomes of free dermal fat graft versus superficial musculoaponeurotic system flap after superficial parotidectomy: randomized clinical trial. BJS Open. 2023 May 5;7(3):zrac173. doi: 10.1093/bjsopen/zrac173.

Reference Type DERIVED
PMID: 37151084 (View on PubMed)

Other Identifiers

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7/2022SURG3B

Identifier Type: -

Identifier Source: org_study_id

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