Dual Task Gait Performance in Pediatric Oncology Patients

NCT ID: NCT04784026

Last Updated: 2021-03-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-03-01

Study Completion Date

2023-03-20

Brief Summary

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Cancer incidence, which is recognized as the leading cause of death in children worldwide, is gradually increasing.

Most studies on children who survive cancer show that the disease and its treatment have side effects and long-term late effects on the musculoskeletal system, physical function, gait and cognitive skills.

Therefore, dual task gait performance, in which cognitive and motor tasks are performed simultaneously, may be affected in pediatric oncology patients. The aim of this study is to compare gait performance in single and dual task conditions in pediatric oncology patients with healthy controls.

Detailed Description

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Cancer incidence, which is recognized as the leading cause of death in children worldwide, is gradually increasing. About 300,000 children aged 0 to 19 are diagnosed with cancer each year, according to the international study where the International Agency for Research on Cancer collected data on neoplasms (malignant and non-malignant) diagnosed in individuals under 20 years of age between 2001-2010.

Most studies on children who survive cancer show that the disease and its treatment have side effects and long-term late effects on the musculoskeletal system, physical function, gait and cognitive skills. According to the study of Beulertz et al. (2016), active ankle dorsiflexion limitation, gait disturbances and decrease in walking efficiency were observed in all pediatric oncology patients, which have an important role in walking, not limited to children with bone tumors and central nervous system tumors.Intensive chemotherapy (eg methotrexate) and the use of radiation are thought to cause damage to cortical and subcortical white matter, resulting in late effects. Symptoms consistent with attention deficit disorder and mental processing speed, working memory, executive function and memory deficits put cancer survivors at an intellectual and academic disadvantage.

Therefore, dual task gait performance, in which cognitive and motor tasks are performed simultaneously, may be affected in pediatric oncology patients. The aim of this study is to compare gait performance in single and dual task conditions in pediatric oncology patients with healthy controls.

Conditions

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Pediatric Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Healthy Control Group

Healthy children who come to Afyonkarahisar Ege Youth and Sports Club Association for the purpose of sports, newly registered and between the ages of 6-18 will constitute the control group of the study.

Gait assessment (single)

Intervention Type OTHER

The single walk will be evaluated with a 10-meter walking test and a G-Walk portable device.

Dual task gait assessment (motor+motor)

Intervention Type OTHER

The dual task gait, 10-meter walking test and a motor (carrying a full water glass) will be combined with the task and evaluated with the G-Walk portable device.

Dual tak gait assessment (motor+cognitive)

Intervention Type OTHER

The dual task gait will be combined with a 10-meter walking test and a cognitive (1-back test) task and evaluated with the G-Walk portable device.

Case Group

The sample of the study will be inpatient and outpatient pediatric patients between the ages of 6-18 who have been diagnosed with cancer in the Pediatric Hematology-Oncology Clinics of Afyonkarahisar Health Sciences University Health Application and Research Center Department of Pediatrics.

Gait assessment (single)

Intervention Type OTHER

The single walk will be evaluated with a 10-meter walking test and a G-Walk portable device.

Dual task gait assessment (motor+motor)

Intervention Type OTHER

The dual task gait, 10-meter walking test and a motor (carrying a full water glass) will be combined with the task and evaluated with the G-Walk portable device.

Dual tak gait assessment (motor+cognitive)

Intervention Type OTHER

The dual task gait will be combined with a 10-meter walking test and a cognitive (1-back test) task and evaluated with the G-Walk portable device.

Interventions

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Gait assessment (single)

The single walk will be evaluated with a 10-meter walking test and a G-Walk portable device.

Intervention Type OTHER

Dual task gait assessment (motor+motor)

The dual task gait, 10-meter walking test and a motor (carrying a full water glass) will be combined with the task and evaluated with the G-Walk portable device.

Intervention Type OTHER

Dual tak gait assessment (motor+cognitive)

The dual task gait will be combined with a 10-meter walking test and a cognitive (1-back test) task and evaluated with the G-Walk portable device.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Healthy control group:

* Being in the age range of 6-18,
* To be physically, cognitively and mentally healthy,
* Open to communication enough to understand questions,
* Speaking and understanding Turkish,
* Approval has been obtained from the child and his / her family for the study and who agrees to participate in the study,

Case group:

* Able to walk alone without any walking aid,
* Open to communication enough to understand questions,
* Speaking and understanding Turkish,
* Approval has been obtained from the child and his / her family for the study and who agrees to participate in the study,
* Children between the ages of 6-18 will be included in the study

Exclusion Criteria

Healthy control group:

* Any orthopedic or neurological impairment that would prevent walking;
* Having any mental disability that prevents cognitive task

Case group:

* Staying in an isolated room or having risk of infection (neutropenic, etc.),
* Any orthopedic or neurological impairment that could prevent walking;
* Having any mental disability that prevents cognitive task,
* Individuals with malignant hypertension or unstable heart disease (eg congestive heart failure) will not be included in the study.
Minimum Eligible Age

6 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Afyonkarahisar Health Sciences University

OTHER

Sponsor Role lead

Responsible Party

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Emel Taşvuran Horata

PhD; Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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EMEL TAŞVURAN HORATA, PhD

Role: PRINCIPAL_INVESTIGATOR

Afyonkarahisar Health Science University

Locations

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Emel Taşvuran Horata

Afyonkarahisar, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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EMEL TAŞVURAN HORATA, PhD

Role: CONTACT

05547759663

Facility Contacts

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EMEL TAŞVURAN HORATA, PhD

Role: primary

+905547759663

Role: backup

Other Identifiers

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2021/144

Identifier Type: -

Identifier Source: org_study_id

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