Impact of Non-fasting on Anxiety in Cataract Surgery

NCT ID: NCT04769856

Last Updated: 2025-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

126 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-05-02

Study Completion Date

2021-11-02

Brief Summary

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The aim of this prospective study was to investigate whether non-fasting recommendation could reduce preoperative anxiety level, incidence of anesthetist interventions, and number of surgical complications in elective cataract surgery patients.

Detailed Description

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Fear of aspiration makes anesthetists reluctant to challenge standard pre-operative fasting guidelines recommending stopping eating solids and drinking clear fluid 6 hours and 2 hours, respectively before anesthesia. However, hunger and thirst exacerbates patients' anxiety, adversely impacts the patient's comfort and satisfaction, and enhances pain response leading to additional need for analgesia.

Patients undergoing non-invasive procedures requiring no or light sedation may benefit from non-fasting recommendations. The need for preoperative fasting in patients undergoing cataract surgery under topical anesthesia remains controversial. Patients are not fasted before standard cataract surgery under local anesthesia in many cataract centers, in accordance with the UK national guideline published in 2012. However, this practice is not supported by a high level of evidence from prospective clinical trials. So far, the lack of international professional consensus on the matter, local practices are based on institutional recommendations obviating the need for starvation in routine cataract surgery under topical anesthesia.

Conditions

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Cataract Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Non-fasting group

Group Type EXPERIMENTAL

State-Trait Anxiety Inventory (STAI) scale

Intervention Type OTHER

State-Trait Anxiety Inventory (STAI) scale

Satisfaction scale

Intervention Type OTHER

Satisfaction scale

Fasting group

Group Type EXPERIMENTAL

State-Trait Anxiety Inventory (STAI) scale

Intervention Type OTHER

State-Trait Anxiety Inventory (STAI) scale

Satisfaction scale

Intervention Type OTHER

Satisfaction scale

Interventions

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State-Trait Anxiety Inventory (STAI) scale

State-Trait Anxiety Inventory (STAI) scale

Intervention Type OTHER

Satisfaction scale

Satisfaction scale

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Information and collection of patient consent
* Age greater than or equal to 18 years
* Affiliation to a social insurance
* Undergoing cataract surgery under topical anesthesia
* Intervention on the 1st eye

Exclusion Criteria

* Refusal to participate
* Language barrier incompatible with the performance of a reliable assessment
* Behavior disorders
* Anesthesia other than topical
* Voluntary control disorder
* Intervention on the 2nd eye
* Taking psychotropic drugs.
* Legal protection regime
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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URC-CIC Paris Descartes Necker Cochin

OTHER

Sponsor Role collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Service Anesthésie Réanimation chirurgicale, Hôpital Cochin

Paris, IDF, France

Site Status

Countries

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France

References

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Guerrier G, Bernabei F, Giannaccare G, Vagge A, Bonnet C, Baillard C, Monnet D, Rothschild PR. The StarvAnx Study-Comparison Between the Effects of Non-fasting Vs. Fasting Strategy on Surgical Outcomes, Anxiety and Pain in Patients Undergoing Cataract Surgery Under Topical Anesthesia: A Randomized, Crossover, Controlled Trial. Front Med (Lausanne). 2022 Jul 13;9:916225. doi: 10.3389/fmed.2022.916225. eCollection 2022.

Reference Type BACKGROUND
PMID: 35911419 (View on PubMed)

Chon T, Ma A, Mun-Price C. Perioperative Fasting and the Patient Experience. Cureus. 2017 May 24;9(5):e1272. doi: 10.7759/cureus.1272.

Reference Type BACKGROUND
PMID: 28652955 (View on PubMed)

Ogino Y, Kakeda T, Nakamura K, Saito S. Dehydration enhances pain-evoked activation in the human brain compared with rehydration. Anesth Analg. 2014 Jun;118(6):1317-25. doi: 10.1213/ANE.0b013e3182a9b028.

Reference Type BACKGROUND
PMID: 24384865 (View on PubMed)

Maltby JR, Hamilton RC. Preoperative fasting guidelines for cataract surgery under regional anaesthesia. Br J Anaesth. 1993 Jul;71(1):167. doi: 10.1093/bja/71.1.167-a. No abstract available.

Reference Type BACKGROUND
PMID: 8343333 (View on PubMed)

Steeds C, Mather SJ. Fasting regimens for regional ophthalmic anaesthesia. A survey of members of the British Ophthalmic Anaesthesia Society. Anaesthesia. 2001 Jul;56(7):638-42. doi: 10.1046/j.1365-2044.2001.02116.x.

Reference Type BACKGROUND
PMID: 11437763 (View on PubMed)

Seet E, Kumar CM, Eke T, Joshi GP. Starving Patients Before Cataract Surgery Under Regional Anesthesia: Needed or Not? Anesth Analg. 2018 Dec;127(6):1448-1451. doi: 10.1213/ANE.0000000000003504. No abstract available.

Reference Type BACKGROUND
PMID: 29863606 (View on PubMed)

Other Identifiers

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APHP201410

Identifier Type: -

Identifier Source: org_study_id

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