An Observational Post-marketing Study Using Commercially Approved Biosense Webster (BWI) Medical Devices for the Treatment of Participants With Cardiac Arrhythmias

NCT ID: NCT04750798

Last Updated: 2026-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

8000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-02-22

Study Completion Date

2037-12-31

Brief Summary

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The purpose of this study is to prospectively collect clinical data evaluating the ongoing safety and performance during routine-use standard cardiac arrhythmia mapping and/or ablation procedures while using commercial Biosense Webster Inc. (BWI) medical devices. Data generated from the study will be used to confirm safety and performance of BWI medical devices in the marketed phase and to expand the body of evidence on the use of these devices and techniques in treatment of cardiac arrhythmias.

Detailed Description

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Conditions

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Arrhythmias, Cardiac

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Participants Diagnosed with Cardiac Arrhythmias

Patients diagnosed with cardiac arrhythmias who are scheduled to undergo an ablation procedure in routine clinical practice for management of their arrhythmia with a BWI therapeutic catheter/Varipulse Catheter/ Dual Energy Thermocool Smarttouch surround flow (SF) catheter will be observed.

Dual Energy THERMOCOOL SMARTTOUCH SF Catheter

Intervention Type DEVICE

Participants treated with the Dual Energy THERMOCOOL SMARTTOUCH SF Catheter in the main study will be part of the DUACURE sub-study. No specific intervention will be observed for this study.

BWI Medical Device

Intervention Type DEVICE

Participants will be treated with commercially approved BWI medical devices following routine clinical practice. No specific intervention will be observed for this study.

Varipulse Catheter

Intervention Type DEVICE

Participants treated with Varipulse Catheter in the main study will be part of the VARIPURE sub-study. No specific intervention will be observed for this study.

Interventions

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Dual Energy THERMOCOOL SMARTTOUCH SF Catheter

Participants treated with the Dual Energy THERMOCOOL SMARTTOUCH SF Catheter in the main study will be part of the DUACURE sub-study. No specific intervention will be observed for this study.

Intervention Type DEVICE

BWI Medical Device

Participants will be treated with commercially approved BWI medical devices following routine clinical practice. No specific intervention will be observed for this study.

Intervention Type DEVICE

Varipulse Catheter

Participants treated with Varipulse Catheter in the main study will be part of the VARIPURE sub-study. No specific intervention will be observed for this study.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Diagnosed with paroxysmal or persistent Atrial Fibrillation (AF) or supraventricular tachycardia (SVT) or ventricular tachycardia (VT) and scheduled to undergo an ablation procedure for management of their arrhythmia with a per-protocol defined BW therapeutic catheter
* Able and willing to comply with all pre, post and follow-up testing and requirements as per hospital standard of care
* Signed patient informed consent form (ICF) as applicable per local regulation

Exclusion Criteria

* Currently participating in an interventional (drug, device, biologic) clinical trial
* Life expectancy of less than 12-months
* Presenting any contraindication for the use of BWI commercially approved medical devices, as indicated in the respective user manuals
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Biosense Webster, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Biosense Webster, Inc. Clinical Trial

Role: STUDY_DIRECTOR

Biosense Webster, Inc.

Locations

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Medical University of Graz

Graz, , Austria

Site Status RECRUITING

Ordensklinikum Linz GMBH

Linz, , Austria

Site Status RECRUITING

OLV Aalst

Aalst, , Belgium

Site Status RECRUITING

AZ Sint-Jan Brugge

Bruges, , Belgium

Site Status RECRUITING

CHU Saint-Pierre

Brussels, , Belgium

Site Status RECRUITING

UZ Antwerp

Edegem, , Belgium

Site Status RECRUITING

Jessa Hospital

Hasselt, , Belgium

Site Status RECRUITING

UZ Brussels

Jette, , Belgium

Site Status RECRUITING

ASBL CHU HELORA Hôpital de La Louvière site Jolimont

La Louvière, , Belgium

Site Status RECRUITING

Aarhus University Hospital

Aarhus, , Denmark

Site Status RECRUITING

Rigshospitalet

Copenhagen, , Denmark

Site Status RECRUITING

Les Hospices Civils de Lyon

Lyon, , France

Site Status RECRUITING

Hôpital Saint Joseph de Marseille

Marseille, , France

Site Status RECRUITING

Institut Mutualiste Montsouris

Paris, , France

Site Status RECRUITING

Centre Hospitalier Universitaire de Bordeaux

Talence, , France

Site Status RECRUITING

Rhön-Klinikum Campus Bad Neustadt

Bad Neustadt an der Saale, , Germany

Site Status RECRUITING

Herz- und Diabeteszentrum NRW, University Hospital of the Ruhr University Bochum

Bad Oeynhausen, , Germany

Site Status RECRUITING

Segeberger Kliniken

Bad Segeberg, , Germany

Site Status RECRUITING

Alfried Krupp Hospital

Essen, , Germany

Site Status RECRUITING

Cardioangiologisches Centrum Bethanien (CCB)

Frankfurt, , Germany

Site Status RECRUITING

German Heart Centre Munich

Munich, , Germany

Site Status RECRUITING

Mater Private Heart and Vascular Centre

Dublin, , Ireland

Site Status RECRUITING

Shaare Zedek Medical Center

Jerusalem, , Israel

Site Status RECRUITING

Tel Aviv Sourasky Medical Center

Tel Aviv, , Israel

Site Status RECRUITING

Ospedale Generale Regionale "F. Miulli"

Acquaviva delle Fonti, , Italy

Site Status RECRUITING

IRCCS Policlinico San Donato

Milan, , Italy

Site Status RECRUITING

Clinical Trial Center Maastricht

Maastricht, , Netherlands

Site Status RECRUITING

Erasmus University Medical Center

Rotterdam, , Netherlands

Site Status RECRUITING

Hospital de Santa Cruz

Carnaxide, , Portugal

Site Status RECRUITING

INSELSPITAL Universitätsspital Bern

Bern, , Switzerland

Site Status RECRUITING

Glenfield Hospital

Leicester, , United Kingdom

Site Status RECRUITING

St. Bartholomew's Hospital

London, , United Kingdom

Site Status COMPLETED

St George's Hospital

London, , United Kingdom

Site Status RECRUITING

Royal Brompton Hospital

London, , United Kingdom

Site Status RECRUITING

Countries

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Austria Belgium Denmark France Germany Ireland Israel Italy Netherlands Portugal Switzerland United Kingdom

Central Contacts

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Nathalie Macours

Role: CONTACT

+32 479 97 05 05

Liesbeth Gorissen

Role: CONTACT

Other Identifiers

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BWI_2019_05

Identifier Type: -

Identifier Source: org_study_id

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