Effect of Lighting Supplementation on Daytime Cognition

NCT ID: NCT04745312

Last Updated: 2022-02-18

Basic Information

• Recruitment Status: UNKNOWN
• Clinical Phase: NA
• Total Enrollment: 16 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2021-03-01
• Study Completion Date: 2022-03-01

Brief Summary

The aim of the study is to examine the efficacy of supplementing sub-optimal ambient room lighting with a task lamp on working memory and procedural learning.

Conditions

Non-visual Effects of Light

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: BASIC_SCIENCE
• Blinding Strategy: NONE

Study Groups

Ambient light

Fluorescent ambient lighting

Group Type: ACTIVE_COMPARATOR

Visible light

Intervention Type: DEVICE

Ambient room lighting will be supplemented with additional light from a task lamp.

Ambient light plus task lamp

Fluorescent ambient lighting plus task lamp

Group Type: EXPERIMENTAL

Visible light

Intervention Type: DEVICE

Ambient room lighting will be supplemented with additional light from a task lamp.

Interventions

Visible light

Ambient room lighting will be supplemented with additional light from a task lamp.

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Aged between 18-30 years;
• Healthy (no medical, psychiatric or sleep disorders;
• Non-smoking for at least 6 months;
• Body Mass Index of >18 or <30 kg/m2;
• Able to maintain 7-hour consistent sleep schedule during the study
• Able to refrain from caffeine, alcohol, medication and supplements during the study

Exclusion Criteria

• History of alcohol or substance abuse;
• positive result on drugs of abuse urine toxicology;
• Current or past history of sleep disorders, including but not limited to obstructive sleep apnea, narcolepsy, insomnia, or any significant sleep complaint
• Psychiatric disorder, or first degree relative with a psychiatric disorder
• Recent acute or chronic medical disorder
• Use of drugs or medication (birth control OK) likely to affect sleep, alertness or light sensitivity, as determined by the investigators
• Visual disorder, including but not limited to color blindness, or family history of glaucoma
• Pregnancy or lactation
• Shift work (> 2 nights / week in the last 3 months and not during the study)
• Transmeridian travel (2 or more time zones) in the past 3 months
• Any other reason as determine by the Principal Investigator

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 30 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Brigham and Women's Hospital

OTHER

Sponsor Role: lead

Responsible Party

Shadab A Rahman

Associate Neuroscientist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Shadab A Rahman, PhD, MPH

Role: PRINCIPAL_INVESTIGATOR

Brigham and Women's Hospital

Locations

Brigham and Women's Hospital

Boston, Massachusetts, United States

Countries

United States

References

Grant LK, Crosthwaite PC, Mayer MD, Wang W, Stickgold R, St Hilaire MA, Lockley SW, Rahman SA. Supplementation of ambient lighting with a task lamp improves daytime alertness and cognitive performance in sleep-restricted individuals. Sleep. 2023 Aug 14;46(8):zsad096. doi: 10.1093/sleep/zsad096.

Reference Type: DERIVED

PMID: 37026184 (View on PubMed)

Other Identifiers

2020A011565

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

2019P000900

Identifier Type: -

Identifier Source: org_study_id