Impact of Anti-TNF, Vedolizumab and Tofacitinib on Aortic Stiffness, Carotid Intima-media Thickness and Cardiovascular Risk of Patients With Ulcerative Colitis
NCT ID: NCT04743518
Last Updated: 2025-05-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE4
100 participants
INTERVENTIONAL
2021-02-02
2025-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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anti-TNF
Aortic pulse wave velocity
Aortic pulse wave velocity (aPWV) is a measure of aortic stiffness
carotid intima media thickness (CIMT)
carotid intima media thickness (CIMT)
vedolizumab
Aortic pulse wave velocity
Aortic pulse wave velocity (aPWV) is a measure of aortic stiffness
carotid intima media thickness (CIMT)
carotid intima media thickness (CIMT)
tofacitinib
Aortic pulse wave velocity
Aortic pulse wave velocity (aPWV) is a measure of aortic stiffness
carotid intima media thickness (CIMT)
carotid intima media thickness (CIMT)
Interventions
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Aortic pulse wave velocity
Aortic pulse wave velocity (aPWV) is a measure of aortic stiffness
carotid intima media thickness (CIMT)
carotid intima media thickness (CIMT)
Eligibility Criteria
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Inclusion Criteria
* Patient older than 18 years,
* Initiating a treatment by infliximab, adalimumab, golimumab, vedolizumab or tofacitinib,
* Written informed consent.
Exclusion Criteria
* Patients with a cardiovascular event such as myocardial infarction and stroke,
* Diabetic patient,
* Pregnant women,
* Minor
* people unable to give their consent to participate
18 Years
ALL
No
Sponsors
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Centre Hospitalier Universitaire, Amiens
OTHER
Responsible Party
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Locations
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CHU Amiens
Amiens, , France
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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PI2020_843_0114
Identifier Type: -
Identifier Source: org_study_id
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