Neuroimaging Findings in Patients With COVID-19

NCT ID: NCT04734223

Last Updated: 2021-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

436 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-01

Study Completion Date

2020-12-31

Brief Summary

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This study aimed to discuss the neuroimaging findings and indications, epidemiological data, laboratory values, and the relationship of these variables with mortality in patients with COVID-19.

Detailed Description

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COVID-19 can present as neurological symptoms such as anosmia, headache, taste perversion, dizziness, syncope, and altered state of consciousness. It has been reported in previous studies that thromboembolic ischemic and hemorrhagic strokes associated with COVID-19 have been observed in the early period. It has been suggested that conditions characterized by neurological sequelae, such as encephalitis and encephalopathy, ataxic seizures, Guillain-Barré syndrome (GBS), demyelinating diseases, and neuromuscular disorders may occur in the longer term.In the present study, the investigators aimed to reveal the findings of neuroimaging analyses performed in patients followed up with a diagnosis of COVID-19 who had neurological symptoms, discuss the relationship of these findings with laboratory and epidemiological data, and emphasize that CNS involvement in these patients should not be overlooked. In this study, 436 patients with COVID-19 who underwent at least one neuroimaging procedure during April 2020-December 2020 due to neurological symptoms and whose diagnosis was confirmed by reverse transcriptase-polymerase chain reaction test were included. Although computed tomography was predominantly used for imaging, magnetic resonance imaging was also used when necessary. The patients were grouped based on imaging findings, and statistical evaluations were made between the groups.

Conditions

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Neuroimaging COVID-19

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Group 1

The first group consisted of 46 patients whose neuroimaging findings demonstrated acute/subacute infarction, bleeding, encephalitis, and venous sinus thrombosis

Neuroimaging Findings in Patients With COVID-19

Intervention Type DIAGNOSTIC_TEST

MR and BT Imaging

Group 2

The 2nd group (N=390) was obtained by subtracting the 1st group from all cases.

Neuroimaging Findings in Patients With COVID-19

Intervention Type DIAGNOSTIC_TEST

MR and BT Imaging

Group 3

The third group (N = 189) consisted of patients of the first group and patients with chronic ischemic changes observed in neuroimaging

Neuroimaging Findings in Patients With COVID-19

Intervention Type DIAGNOSTIC_TEST

MR and BT Imaging

Group 4

The 4th group (N=247) was obtained by subtracting the 3rd group from all cases.

Neuroimaging Findings in Patients With COVID-19

Intervention Type DIAGNOSTIC_TEST

MR and BT Imaging

Interventions

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Neuroimaging Findings in Patients With COVID-19

MR and BT Imaging

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* COVID-19 RT-PCR positivity-
* older than 18 years old

Exclusion Criteria

* younger than 18 years old
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

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Seyhmus Kavak

MD, Radiologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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ŞEYHMUS KAVAK, MD

Role: PRINCIPAL_INVESTIGATOR

SAGLIK BİLİMLERİ ÜNİVERSİTESİ TRAINING AND RESEARCH HOSPITAL H

Locations

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Sağlik Bilimleri Üniversitesi Training and Research Hospital

Diyarbakır, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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09.25.2020/587

Identifier Type: -

Identifier Source: org_study_id

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