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NeuroCovid - a Study of Intensive Care-requiring Covid-19 Patients

NCT ID: NCT04578197

Last Updated: 2020-10-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-18

Study Completion Date

2022-11-30

Brief Summary

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Critically ill patients requiring intensive care suffer to a large extent from cognitive deficits involving higher brain functions that primarily affect memory, learning and the ability to concentrate. While the background to this effect is not fully understood, there are growing evidence to support mechanisms related to neuro inflammation and changes in blood flow with concomitant ischemic brain damage. Patients with covid-19 often suffer from severe inflammatory activity with an increased risk of coagulation abnormalities and brain damage. Covid-19 patients requiring intensive care develope more severe impairment of neurological and cognitive function than critically ill intensive care patients who have not covid-19. This project therefore aims to map the link between inflammation, immunology and coagulation systems as well as biochemical and structural changes in the brain with cognitive effects in patients in intensive care for covid-19.

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Detailed Description

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Conditions

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Covid19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age ≥18 years
* Need for Intensive care
* Positive PCR test for SARS-CoV-2

Exclusion Criteria

* None
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Karolinska Institutet

OTHER

Sponsor Role collaborator

Karolinska University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Lars I Eriksson

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Lars I Eriksson, Professor

Role: PRINCIPAL_INVESTIGATOR

Karolinska University Hospital

Locations

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Karolinska Universitetssjukhuset Solna

Stockholm, , Sweden

Site Status RECRUITING

Countries

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Sweden

Central Contacts

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Lars I Eriksson, Professor

Role: CONTACT

[email protected]
+46-8-51770000

Mia Kivipelto, Professor

Role: CONTACT

[email protected]

Facility Contacts

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Lars I Eriksson, Prof

Role: primary

[email protected]
+46-8-51770000

Other Identifiers

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Dnr 2020-02760

Identifier Type: -

Identifier Source: org_study_id

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