Effects of External Neuromuscular Electrical Stimulation in Women With Urgency Urinary Incontinence

NCT ID: NCT04727983

Last Updated: 2023-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

34 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-01

Study Completion Date

2022-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To reveal the effects of Neuromuscular Electrical Stimulation (NMES) applied over the thigh on incontinence symptoms, pelvic floor muscle function, bladder function, quality of life and sexual function in women with urge urinary incontinence (UUI) symptoms. Our goal is to contribute to the literature on electrical stimulation (ES) applications used in UUI treatment.

Female patients aged 18-65 years with UUI symptoms will be included in the study. Patients will be divided into 2 groups randomly. The first group will be given Neuromuscular Electrical Stimulation (NMES) and lifestyle suggestions (LSS) (NMES group). The second group will be given sham NMES in addition to LSS (SHAM ES group). Information about bladder irritants, voiding posture and behavior, weight control and pelvic floor muscle training will be provided in the LSS. ES applications will be performed 3 days a week for 30 minutes per session for 8 weeks. All participants will be evaluated pretreatment, after the 4th week and posttreatment. Pelvic floor muscle function will evulate with the Modified Oxford Scale. In addition, women's bladder function with the urinary diary for 3 days, incontinence symptoms with the International Incontinence Consultation Questionnaire-Short Form (ICIQ-SF) and the Coital Incontinence Score (CIS), quality of life with the King Health Questionnaire (KHQ) and Sexual Function will be evaluated with Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12). At the end of the 8th week, both the Subjective perception of improvement and treatment satisfaction of the patients will be questioned

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Our study will be carried out with female patients between the ages of 18-65 who have Urge urinary Incontinence (UUI) symptoms and applied to the Recep Tayyip Erdogan University Training and Research Hospital, Gynecology and Obstetrics Policlinic. Inclusion criterias are; who do not want to use medication, who do not benefit from medication for a long time or who do not use any medication. Exclusion criterias are; Those with any malignant conditions, those with neurological disease, those with infection, pregnant women, those with pelvic organ prolapse above stage 2 according to the POP-Q staging, those with cardiac implants and pacemakers, those with cardiac arrhythmia, those with urinary retention, those with sensory loss, copper coil intrauterine those who wear a vehicle, patients with metal implants and patients with communication and cooperation problems.

Before starting the study, all participants will be questioned about demographic and physical characteristics, medical, obstetric, gynecological and urological history and drug use. After these evaluations, sensory and reflex evaluations will be made. Sensory assessment will be performed with a light touch test to the hip circumference and pelvic floor muscles. In reflex evaluation, anal and bulbocavernous reflexes will be checked. All of the applications will be carried out by Specialist Physiotherapist Tuğba Birben under the supervision of Specialist Gynecologist Physician Beril Gürlek.

Our study will be in 2 groups. It is estimated that the number of people will consist of 40 volunteers, with 20 patients for each group. The sample size will be determined after the pilot study. Patients who were diagnosed with UUI, met the study criteria and accepted to be included in the study, within a period of 9 months after the approval of the ethics committee, with the four-block randomization method, via the website https://www.sealedenvelope.com/simple-randomiser/v1/lists will be included in groups according to randomization. lifestyle suggestions (LSS)+ NMES (NMES group) will be applied to the first group and LSS + SHAM Electrical Stimulation (SHAM ES group) will be applied to the second group. Each group will be included in the 8-week treatment program for 30 minutes, 3 days a week.

Pelvic floor muscle function of all participants will be evaluated with the Modified Oxford Scale before treatment, at the end of the 4th week and after treatment. In addition, women's bladder function with the urinary diary, incontinence symptoms with the International Incontinence Consultation Questionnaire-Short Form (ICIQ-SF) and the Coital Incontinence Score (CIS), quality of life with the King Health Questionnaire (KHQ) and Sexual Function will be evaluated with Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12). At the end of the 8th week, both the Subjective perception of improvement and treatment satisfaction of the patients will be questioned.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Physiotherapy Women's Health Urge Incontinence Electrical Stimulation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Patients will be divided into 2 groups randomly.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
This study was planned single blinded randomized control.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Pelvic Floor Muscle Function

Pelvic floor muscle function will be evulated with the Modified Oxford Scale

Group Type NO_INTERVENTION

No interventions assigned to this group

Bladder function

Bladder function will be evulated with the urinary diary for 3 days

Group Type NO_INTERVENTION

No interventions assigned to this group

Incontinence Symptoms

Incontinence Symptoms will be evulated with The International Incontinence Consultation Questionnaire-Short Form (ICIQ-SF) and the Coital Incontinence Score (CIS)

Group Type NO_INTERVENTION

No interventions assigned to this group

Quality of Life

Quality of life will be evulated with the King Health Questionnaire (KHQ)

Group Type NO_INTERVENTION

No interventions assigned to this group

Sexual Function

Sexual Function will be evaluated with Pelvic Organ Prolapse / Urinary Incontinence Sexual Questionnaire (PISQ-12).

Group Type NO_INTERVENTION

No interventions assigned to this group

NMES group

The first group will be given Neuromuscular Electrical Stimulation (NMES) and lifestyle suggestions (LSS)

Group Type EXPERIMENTAL

Electrotherapy

Intervention Type DEVICE

The first group will be given Neuromuscular Electrical Stimulation (NMES) and lifestyle suggestions (LSS) (NMES group)

SHAM ES group

The second group will be given sham NMES in addition to LSS

Group Type SHAM_COMPARATOR

Sham Electrotherapy

Intervention Type DEVICE

The second group will be given sham NMES in addition to LSS (SHAM ES group)

End of Treatment Special Evaluations

Subjective perception of improvement and treatment satisfaction of the patients will be questioned

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Electrotherapy

The first group will be given Neuromuscular Electrical Stimulation (NMES) and lifestyle suggestions (LSS) (NMES group)

Intervention Type DEVICE

Sham Electrotherapy

The second group will be given sham NMES in addition to LSS (SHAM ES group)

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* who do not want to use medication,
* who do not benefit from medication for a long time
* who do not use any medication

Exclusion Criteria

* Those with any malignant conditions,
* those with neurological disease,
* those with infection,
* pregnancy,
* those with pelvic organ prolapse above stage 2 according to the POP-Q staging,
* those with cardiac implants and pacemakers,
* those with cardiac arrhythmia,
* those with urinary retention,
* those with sensory loss,
* copper coil intrauterine those who wear a vehicle,
* patients with metal implants
* patients with communication and cooperation problems
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Recep Tayyip Erdogan University Training and Research Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

TUĞBA BİRBEN

Tugba Birben

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

TUGBA BIRBEN, MSc

Role: STUDY_DIRECTOR

Recep Tayyıp Erdogan University Guneysu Vocational School of Physical Therapy and Rehabilitation

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Recep Tayyıp Erdogan University Guneysu Vocational School of Physical Therapy and Rehabilitation

Rize, Guneysu, Turkey (Türkiye)

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Turkey (Türkiye)

References

Explore related publications, articles, or registry entries linked to this study.

Kurt TB, Yilmaz B, Celenay ST. Effects of external neuromuscular electrical stimulation in women with urgency urinary incontinence: a randomized sham-controlled study. World J Urol. 2024 Jul 21;42(1):423. doi: 10.1007/s00345-024-05126-7.

Reference Type DERIVED
PMID: 39033475 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2020/07 decision, 21 protocol

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.