VDR SNPs & 25OHD Correlated With Dyslipidemia

NCT ID: NCT04707612

Last Updated: 2021-01-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1987 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-07-01

Study Completion Date

2016-10-31

Brief Summary

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The project was aimed to explore the associations of single nucleotide polymorphisms (SNPs) of vitamin D receptor gene with specific circulating lipids in adult Chinese. The circulating 25-hydroxyvitamin D concentration was also tested to explore its interactions with SNPs in the associations.

Detailed Description

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Conditions

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Dyslipidemias Single Nucleotide Polymorphism

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

CROSS_SECTIONAL

Interventions

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No intervention.

No intervention.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 1\) ≥ 20 years old Han Chinese;
* 2\) living in Shenzhen for \> 2 years;
* 3\) free of liver diseases, renal diseases, and any cancers in the past 6 months; and
* 4\) not in pregnancy for women.

Exclusion Criteria

* 1\) had severe organic diseases,
* 2\) had acute infection symptoms, allergic diseases, and malignant tumors,
* 3\) had a family history of genetic diseases,
* 4\) took VD supplements in the past 6 months,
* 5\) took medicines to control lipid levels within 12 hours, or
* 6\) took diuretics, did strenuous exercise, or overate within 24 hours before the test.
Minimum Eligible Age

20 Years

Maximum Eligible Age

81 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Sun Yat-sen University

OTHER

Sponsor Role collaborator

Shenzhen Center for Chronic Disease Control

OTHER

Sponsor Role lead

Responsible Party

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Zhou Ji-Chang

Director of Molecular Biology Laboratory

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shenzhen Center for Chronic Disease Control

Shenzhen, Guangdong, China

Site Status

Countries

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China

Other Identifiers

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QLS2015

Identifier Type: -

Identifier Source: org_study_id

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