The Relationship Between Vitamin D, Fingernail Thickness and Bone Density

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Study Classification

INTERVENTIONAL

Brief Summary

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Vitamin D deficiency is common in the elderly and contributes to the increased incidence of falls, hip fracture and depression in this population. An unknown number of elderly have vitamin D resistance resulting in a functional vitamin D deficiency state. Because there are no simple procedures or blood tests that identify vitamin D resistance, its prevalence and contribution to disability in the elderly is unknown. Our inability to screen for this condition precludes our ability to initiate and monitor treatment.

Previous studies indicate that fingernail thickness correlates with vitamin D status and may therefore provide a simple cost effective procedure to not only identify patients with vitamin D deficiency but also, those with vitamin D resistance. This procedure may also provide a way to monitor an individual's response to treatment.

This study is designed to demonstrate the association between fingernail thickness and vitamin D status.

Detailed Description

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Conditions

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Osteoporosis

Keywords

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Vitamin D resistance

Study Design

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Allocation Method

RANDOMIZED

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

DOUBLE

Interventions

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Vitamin D

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* females 25-75 years of age with no known bone disorders

Exclusion Criteria

* history of vertebral fractures or nonvertebral fractures without trauma
* prescription medications for prevention of osteoporosis (including vitamin D other than multivitamin and estrogen)
* history of malignancy other than basal cell or squamous cell cancer of the skin
* use of steroids or anticonvulsants in the 6 months prior to enrollment

Minimum Eligible Age

25 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Locations

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4488 Forest Park, Suite 201

St Louis, Missouri, United States

Site Status

Countries

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United States

Other Identifiers

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M01RR000036

Identifier Type: NIH

Identifier Source: secondary_id

View Link

NCRR-M01RR00036-0754

Identifier Type: -

Identifier Source: org_study_id