Extracellular Vesicles as Biomarkers for Chronic Renal Failure
NCT ID: NCT04700631
Last Updated: 2025-09-19
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
143 participants
INTERVENTIONAL
2021-01-01
2023-07-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
OTHER
NONE
Study Groups
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healthy subject
healthy subjects : no medical history, in particular cardiovascular, without drug treatment, without proteinuria, normal BMI
urinary extracellular vesicle concentration
urinary extracellular vesicle concentration will be determined in urine samples from CRF and healthy patients
blood sample
blood sample in order to determine creatin level
CRF patients
CRF patients : eGFR estimated according to the MRDR formula less than 89 mL/min/1,73m²
urinary extracellular vesicle concentration
urinary extracellular vesicle concentration will be determined in urine samples from CRF and healthy patients
blood sample
blood sample in order to determine creatin level
Interventions
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urinary extracellular vesicle concentration
urinary extracellular vesicle concentration will be determined in urine samples from CRF and healthy patients
blood sample
blood sample in order to determine creatin level
Eligibility Criteria
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Inclusion Criteria
* healthy subjects : no medical history, in particular cardiovascular, without drug treatment, without proteinuria, normal BMI
* CRF patients : eGFR estimated according to the MRDR formula less than 89 mL/min/1,73m²
Exclusion Criteria
* renal transplant patients
18 Years
ALL
No
Sponsors
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Centre Hospitalier Universitaire, Amiens
OTHER
Responsible Party
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Locations
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CHU Amiens
Amiens, , France
Countries
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References
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Jacob V, de Berny Q, Brazier F, Presne C, Lion J, Ouled-Haddou H, Metzinger-Le Meuth V, Choukroun G, Metzinger L, Guillaume N. Quantification of Urine and Plasma Levels of Extracellular Vesicles in a Cohort of Kidney Transplant Recipients and Chronic Kidney Disease Patients. Int J Mol Sci. 2025 Apr 11;26(8):3635. doi: 10.3390/ijms26083635.
Other Identifiers
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PI2020_843_0104
Identifier Type: -
Identifier Source: org_study_id
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