Long-term Effects of COVID-19 in Adolescents

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

516 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-01-06

Study Completion Date

2022-06-24

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The overarching objective for this prospective cohort study of COVID-19 in adolescents is to study the long-term effects, with particular emphasis on post-infectious chronic fatigue. A total of 500 individuals with a SARS-CoV-2 positive test will be enrolled in the acute phase of COVID-19 and followed for 6 months. A total of 100 individuals with SARS-CoV-2 negative test will be included during the same time period as a control group. Investigations include autonomic, pulmonary and cognitive assessement; a questionnaire charting symptoms, emotionality, personality, loneliness, life events and demographics; and extensive biobanking including genetic markers, viable PBMC, urine, feces and hair. A subgroup of 40 SARS-CoV-2 positive and 20 SARS-CoV-2 negative individuals will also undergo detailed cardiological examination by echocardiography. Primary endpoints are fatigue at 6 months as assessed by the Chalder Fatigue Scale and post-COVID-19 syndrome cases at 6 months according to the WHO definition

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Consequences of COVID-19 Infection for Child Health and Wellbeing: Protocol for a Prospective, Observational, Longitudinal Study in Children

NCT05799508

Long COVID

UNKNOWN

Post COVID-19 Complications in Children

NCT05745974

Post COVID-19 Condition

UNKNOWN

The Long-term Impact of Invasive Meningococcal Disease in Australian Adolescents and Young Adults

NCT03798574

Meningococcal Infections Neisseria Meningitis Sepsis Neisseria Infection

COMPLETED

Coronavirus Infection in Primary or Secondary Immunosuppressed Children and Adults.

NCT04382508

Immune Suppression Immune Deficiency Infection +2 more

UNKNOWN

Serological Profile of Children and Young Adolescents With at Least One COVID-19 Diagnosed Family Member

NCT04649944

Covid19

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Covid19

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

SARS-CoV-2 positive

No active intervention (observational only)

Intervention Type OTHER

No active intervention (observational only)

SARS-CoV-2 negative

No active intervention (observational only)

Intervention Type OTHER

No active intervention (observational only)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

No active intervention (observational only)

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Positive SARS-CoV-2 test/negative SARS-CoV-2 test
* Age 12 - 25 years
* Living in the counties of Oslo or Viken, Norway
* \< 28 days since onset of first symptom