Hot and Cold Compress in Hemodialysis

NCT ID: NCT04681521

Last Updated: 2020-12-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

69 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-02-01

Study Completion Date

2020-11-20

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Aims and objectives. To examine and compare the effects of hot and cold compresses administration on muscle cramps, fatigue, and comfort in hemodialysis (HD) patients.

Background. Muscle cramps and fatigue are common complications in HD patients and reduce patient comfort. Among the nursing interventions stated for the management of these complications in the literature, hot and cold therapy are remarkable. To the best of our knowledge, the present study is the first research up to date that examined and compared the effects of hot and cold compress administrations on abovementioned complications in HD.

Design. This placebo-controlled randomized trial was conducted in two hemodialysis centers between February and October 2020.

Methods. The study sample consisted of 69 patients, stratified and randomly allocated to two intervention groups and placebo group. For patients of each group, the implementation of the study continued for four weeks, 12 HD sessions.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Hemodialysis (HD) is a common renal replacement therapy used in the treatment of End-Stage Renal Disease (ESRD) worldwide. Although HD is a life-saving treatment for people with ESRD, it causes some acute and chronic complications. Muscle cramps and fatigue are two of the most common complications in HD, and these also cause reducing comfort. Management of complications in HD patients and ensuring an optimal comfort level are pivotal for nurses. According to the literature, recommended nursing practices for the management of cramps in HD patients include hot and cold therapy methods. Besides, preventing cramps can improve comfort by reducing fatigue. Therefore, this study aimed to examine and compare the effects of hot and cold compresses administration on muscle cramps, fatigue, and comfort in hemodialysis (HD) patients.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hemodialysis Complication Muscle Spasm Fatigue

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

hemodialysis muscle cramp fatigue comfort nursing care complementary therapies

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

placebo controlled randomized trial
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

HOT THERAPY:GROUP A

Hot Compress Group

Group Type EXPERIMENTAL

Hot and Cold compress, nursing interventions

Intervention Type OTHER

using thermal compress at 38-39 °C (hot) and 15-16 °C (cold) on the distal regions of both lower extremities of the patients

COLD THERAPY:GROUP B

Cold Compress Group

Group Type EXPERIMENTAL

Hot and Cold compress, nursing interventions

Intervention Type OTHER

using thermal compress at 38-39 °C (hot) and 15-16 °C (cold) on the distal regions of both lower extremities of the patients

PLACEBO: GROUP C

Inoperative compress Group

Group Type PLACEBO_COMPARATOR

Hot and Cold compress, nursing interventions

Intervention Type OTHER

using thermal compress at 38-39 °C (hot) and 15-16 °C (cold) on the distal regions of both lower extremities of the patients

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Hot and Cold compress, nursing interventions

using thermal compress at 38-39 °C (hot) and 15-16 °C (cold) on the distal regions of both lower extremities of the patients

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* between the ages of 18-65,
* receiving HD treatment for at least six months,
* three days a week with four-hour sessions
* with blood pressure 120/80 mmHg and higher at the beginning of the HD session,
* did not develop intradialytic hypotension in the first two hours of HD,
* hemoglobin value above 8.0 mg/dL,
* having a stable dry weight for the previous month (less than 2 kg change).

Exclusion Criteria

* receiving intravenous electrolyte replacement during HD session,
* having a condition that prevented hot or cold administration such as diabetic neuropathy, burns, open wounds, and amputation in the lower extremities,
* with an oncological diagnosis or autoimmune disease (rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis, fibromyalgia, etc.),
* refused to participate in the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Hacettepe University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Gülşah Kesik

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Leyla Özdemir, Prof. Dr.

Role: STUDY_DIRECTOR

Hacettepe University

Tolga Yıldırım, Assos. Prof.

Role: STUDY_DIRECTOR

Hacettepe University

Cebrail Cebrailov, M.D.

Role: STUDY_CHAIR

Hacettepe University

Gülseren Çeliksöz, M.D.

Role: STUDY_CHAIR

Betamar Dialysis Center

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hacettepe University

Ankara, None Selected, Turkey (Türkiye)

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Turkey (Türkiye)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

KA-19143

Identifier Type: -

Identifier Source: org_study_id