Early Intervention in Remote Autism (IPAAD)

NCT ID: NCT04660669

Last Updated: 2023-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

90 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-31

Study Completion Date

2025-12-31

Brief Summary

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The Early Start Denver Model (ESDM) has shown its efficiency in the early management of ASD.

The study aims to evaluate the efficiency of a new type of management based on a semi-intensive center-based intervention (8h per week) coupled with a MOOC (Massive Online Open Course: a teaching and learning intervention based on instrumental and interactive teaching situations) for remote parental training/supervision. The goal is to determine if compared to the ESDM reference intervention (15h per week), this type of care can bring, a sufficient improvement in child development course and decreased symptoms of autism in young children, and if it could be, therefore, better suited to the needs of children and their family, bypassing the previously stated obstacles.

Detailed Description

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Conditions

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Early Intervention in Remote Autism

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Group 1 receives 15 hours per week of ESDM intervention from ESDM therapists. The parents benefit from a 20 hour parent training program delivered in the participating center. Group 2 receives 8 hours per week of ESDM intervention from ESDM therapists in addition to whatever community service the parents choose. The parents benefit from a training program remotely delivered via a MOOC platform as well as parental supervision of sessions delivered at home 1 hour per week for the duration of the study.
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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ESDM 15h

This arm receives 15 hours per week of ESDM intervention from ESDM therapists. The parents benefit from a 20 hour parent training program delivered in the participating center.

Group Type OTHER

ESDM intervention

Intervention Type OTHER

Early Start Denver Model (ESDM) intervention with remote parental training/ supervision versus intensive ESDM intervention.

ESDM 8h + MOOC

This arm receives 8 hours per week of ESDM intervention from ESDM therapists in addition to whatever community service the parents choose. The parents benefit from a training program remotely delivered via a MOOC platform as well as parental supervision of sessions delivered at home 1 hour per week for the duration of the study.

Group Type OTHER

ESDM intervention

Intervention Type OTHER

Early Start Denver Model (ESDM) intervention with remote parental training/ supervision versus intensive ESDM intervention.

MOOC

Intervention Type OTHER

Massive Online Open Course: a teaching and learning intervention based on instrumental and interactive teaching situations

Interventions

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ESDM intervention

Early Start Denver Model (ESDM) intervention with remote parental training/ supervision versus intensive ESDM intervention.

Intervention Type OTHER

MOOC

Massive Online Open Course: a teaching and learning intervention based on instrumental and interactive teaching situations

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Diagnosis of ASD based on the Diagnosis and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) criteria;
2. Diagnosis of ASD on the Autism Diagnosis Observation Schedule (ADOS-2) and Autism Diagnosis Interview (ADIR) for toddlers (we will include children above or equal to 13, which is the research cut-off);
3. Aged between 15 and 36 months;
4. DQ of 30 or above at the MSEL
5. Sign informed consent form by both parents

Exclusion Criteria

1. A neurodevelopmental disorder with known etiology (e.g. fragile X syndrome, Rett syndrom)
2. Significant sensory or motor impairment
3. Major physical problems such as a chronic serious health condition
4. History of a serious head injury and/or neurologic disease
5. Seizures at time of entry
6. Use of psychoactive medications (7 ) Families unavailable for the intervention and the followup over a period of 12 months

(8) Impossibility for family to have access to the MOOC
Minimum Eligible Age

15 Months

Maximum Eligible Age

36 Months

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Brest

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nathalie LAVENNE

Role: PRINCIPAL_INVESTIGATOR

CHRU BREST

Locations

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CH Réné-Dubos

Cergy-Pontoise, , France

Site Status

CHU Le Havre

Le Havre, , France

Site Status

CH Limoges

Limoges, , France

Site Status

CHU Nantes

Nantes, , France

Site Status

Countries

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France

Central Contacts

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Nathalie LAVENNE, Doctor

Role: CONTACT

02 98 01 50 47

Adrien CLARYSSE

Role: CONTACT

02 29 02 00 88

Facility Contacts

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Erwan VION

Role: primary

01 30 75 48 30

Karine LEYDIER

Role: primary

02 32 73 38 37

Françoise DUPONT

Role: primary

02 28 08 84 90

Other Identifiers

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IPAAD (29BRC19.0279)

Identifier Type: -

Identifier Source: org_study_id

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